Foscarnet, Phosphonoformic acid
cas: 4428-95-9 — see every product listed under this CAS number, including other names
Foscarnet, Phosphonoformic acid (CAS 4428-95-9) is a chemical reagent available from Chemat. Available pack sizes: on request. Offered by: Chemat Brand.
| brand | Chemat Brand |
|---|---|
| catalog number | RM-F151900 |
| cas | 4428-95-9 |
| size | on request |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Phosphonoformic acid is phosphoric acid in which one of the hydroxy groups is replaced by a carboxylic acid group. It is used as the trisodium salt as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity. It has a role as a geroprotector, an antiviral drug, a HIV-1 reverse transcriptase inhibitor and a sodium-dependent Pi-transporter inhibitor. It is a member of phosphonic acids, a carboxylic acid and a one-carbon compound. It is functionally related to a formic acid and a phosphonic acid. It is a conjugate acid of a phosphonatoformate and a phosphonoformate(2-).
Source: ChEBI
| Molecular formula | CH3O5P |
|---|---|
| Molecular weight | 126.01 g/mol |
| IUPAC name | phosphonoformic acid |
| InChIKey | ZJAOAACCNHFJAH-UHFFFAOYSA-N |
| SMILES | C(=O)(O)P(=O)(O)O |
Computed by PubChem (NCBI)