Fosinopril impurity C

cas: 474519-28-3 — see every product listed under this CAS number, including other names

Fosinopril impurity C (CAS 474519-28-3) is a chemical reagent available from Chemat. Available pack sizes: -. Offered by: Sigma-Aldrich.

brandSigma-Aldrich
catalog numberY0001230
cas474519-28-3
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Available pack sizes

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Sigma-Aldrich - 695.70 Pln
Structural formula: {0} (CAS {1})

Fosinopril is a phosphinate ester-containing N-acyl derivative of (4S)-cyclohexyl-L-proline. It is used for the treatment of hypertension and heart failure. A pro-drug, it is hydrolysed in vivo to the corresponding phosphininc acid, fosinoprilat, which is the active metabolite. It has a role as an EC 3.4.15.1 (peptidyl-dipeptidase A) inhibitor, an antihypertensive agent and a prodrug. It is a phosphinic ester and a L-proline derivative. It is functionally related to a fosinoprilat. It is a conjugate acid of a fosinopril(1-).

Source: ChEBI

Identity
Molecular formulaC30H46NO7P
Molecular weight563.7 g/mol
IUPAC name(2S,4S)-4-cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid
InChIKeyBIDNLKIUORFRQP-FKDWWROVSA-N
SMILESCCC(=O)OC(C(C)C)OP(=O)(CCCCC1=CC=CC=C1)CC(=O)N2C[C@@H](C[C@H]2C(=O)O)C3CCCCC3

Computed by PubChem (NCBI)

Synonyms: Fosinopril impurity C, FOSINOPRIL EP IMPURITY C, starbld0017934, BIDNLKIUORFRQP-FKDWWROVSA-N, FOSINOPRIL SODIUM IMPURITY C [EP IMPURITY]
Related forms of this compound
(2S,4S)-4-cyclohexyl-1-[2-[(2-methyl-1-propanoyloxypropoxy)-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid C30H46NO7P
(2S,4S)-4-cyclohexyl-1-[2-[[(1S)-2-methyl-1-propanoyloxypropoxy]-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid C30H46NO7P
(2S,4R)-4-cyclohexyl-1-[2-[[(1S)-2-methyl-1-propanoyloxypropoxy]-(4-phenylbutyl)phosphoryl]acetyl]pyrrolidine-2-carboxylic acid C30H46NO7P