Ivosidenib, 99.89%
cas: 1448347-49-6 — see every product listed under this CAS number, including other names
Ivosidenib, 99.89% (CAS 1448347-49-6) is a chemical reagent available from Chemat. Available pack sizes: 10mM/1mL, 25 mg, 50 mg, 100 mg, 10 mg, 5 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-18767-10mM/1mL |
| cas | 1448347-49-6 |
| size | 10mM/1mL |
| availability | In stock |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 10mM/1mL | 709.79 Pln | |
| MedChemExpress | 25 mg | 1271.71 Pln | |
| MedChemExpress | 50 mg | 1963.67 Pln | |
| MedChemExpress | 100 mg | 3115.38 Pln | |
| MedChemExpress | 10 mg | 825.89 Pln | |
| MedChemExpress | 5 mg | 505.45 Pln |
properties
| delivery time | 1-2 weeks |
|---|---|
| purity | 99.89% |
Ivosidenib is a tertiary carboxamide resulting from the formal condensation of the carboxy group of (2S)-1-(4-cyanopyridin-2-yl)-5-oxopyrrolidine-2-carboxylic acid with the secondary amino group of (2S)-2-(2-chlorophenyl)-N-(3,3-difluorocyclobutyl)-2-[(5-fluoropyridin-3-yl)amino]acetamide. It is approved by the FDA for the treatment of acute myeloid leukemia (AML) in patients with an isocitrate dehydrogenase-1 (IDH1) mutation. It has a role as an EC 1.1.1.42 (isocitrate dehydrogenase) inhibitor and an antineoplastic agent. It is a secondary carboxamide, a tertiary carboxamide, a cyanopyridine, an organofluorine compound, a member of pyrrolidin-2-ones and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C28H22ClF3N6O3 |
|---|---|
| Molecular weight | 583.0 g/mol |
| IUPAC name | (2S)-N-[(1S)-1-(2-chlorophenyl)-2-[(3,3-difluorocyclobutyl)amino]-2-oxoethyl]-1-(4-cyano-2-pyridinyl)-N-(5-fluoro-3-pyridinyl)-5-oxopyrrolidine-2-carboxamide |
| InChIKey | WIJZXSAJMHAVGX-DHLKQENFSA-N |
| SMILES | C1CC(=O)N([C@@H]1C(=O)N(C2=CC(=CN=C2)F)[C@@H](C3=CC=CC=C3Cl)C(=O)NC4CC(C4)(F)F)C5=NC=CC(=C5)C#N |
Computed by PubChem (NCBI)