JTE-607 (free base)
cas: 188791-71-1 — see every product listed under this CAS number, including other names
JTE-607 (free base) (CAS 188791-71-1) is a chemical reagent available from Chemat. Available pack sizes: Get quote. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-110133A-Get quote |
| cas | 188791-71-1 |
| size | Get quote |
| availability | Get quote |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| MedChemExpress | Get quote | price on request |
properties
| delivery time | to confirm by Chemat |
|---|---|
| purity | no data |
JTE-607 free base is a secondary carboxamide resulting from the formal condensation of the carboxy group of 3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzoic acid with the amino group of ethyl L-phenylalaninate. It inhibits cytokine production in human peripheral blood mononuclear cells (PBMC's) without causing immunosuppression. It has a role as a CPSF3 inhibitor, an antineoplastic agent, a prodrug, an anti-inflammatory agent and an apoptosis inducer. It is a secondary carboxamide, a member of benzamides, a dichlorobenzene, an ethyl ester, a member of phenols, an aromatic ether, a N-methylpiperazine and a L-phenylalanine derivative. It is a conjugate base of a JTE-607(2+). It is a tautomer of a JTE-607 zwitterion.
Source: ChEBI
| Molecular formula | C25H31Cl2N3O5 |
|---|---|
| Molecular weight | 524.4 g/mol |
| IUPAC name | ethyl (2S)-2-[[3,5-dichloro-2-hydroxy-4-[2-(4-methylpiperazin-1-yl)ethoxy]benzoyl]amino]-3-phenylpropanoate |
| InChIKey | IPSSXIMJJXSJQB-FQEVSTJZSA-N |
| SMILES | CCOC(=O)[C@H](CC1=CC=CC=C1)NC(=O)C2=CC(=C(C(=C2O)Cl)OCCN3CCN(CC3)C)Cl |
Computed by PubChem (NCBI)
Synonyms:
orb1703316