LOXO-305

cas: 2101700-15-4 — see every product listed under this CAS number, including other names

LOXO-305 (CAS 2101700-15-4) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 1mg, 2mg, 5mg. Offered by: Biosynth.

brandBiosynth
catalog numberBL180882-10mg
cas2101700-15-4
size10mg
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properties

categoryLife Sciences
sub-category 1Ligands
sub-category 2Enzyme Modulators
purityNo data
delivery time1-2 weeks
Structural formula: {0} (CAS {1})

Pirtobrutinib is a secondary carboxamide resulting from the formal condensation of the carboxy group of 5-fluoro-2-methoxybenzoic acid with the amino group of 5-amino-3-[4-(aminomethyl)phenyl]-1-[(2S)-1,1,1-trifluoropropan-2-yl]-1H-pyrazole-4-carboxamide. It is a BTK inhibitor used for the treatment of adult patients with chronic lymphocytic leukemia or small lymphocytic lymphoma. It has a role as an antineoplastic agent, an apoptosis inducer and an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a primary carboxamide, a secondary carboxamide, a member of benzamides, a monomethoxybenzene, a member of pyrazoles, an organofluorine compound, a primary amino compound and a member of monofluorobenzenes.

Source: ChEBI

Identity
Molecular formulaC22H21F4N5O3
Molecular weight479.4 g/mol
IUPAC name5-amino-3-[4-[[(5-fluoro-2-methoxybenzoyl)amino]methyl]phenyl]-1-[(2S)-1,1,1-trifluoropropan-2-yl]pyrazole-4-carboxamide
InChIKeyFWZAWAUZXYCBKZ-NSHDSACASA-N
SMILESC[C@@H](C(F)(F)F)N1C(=C(C(=N1)C2=CC=C(C=C2)CNC(=O)C3=C(C=CC(=C3)F)OC)C(=O)N)N

Computed by PubChem (NCBI)

Synonyms: Pirtobrutinib, JAYPIRCA, BTK Inhibitor LOXO-305, Pirtobrutinib [USAN], BTK inhibitor 16, pirtobrutinibum, PIRTOBRUTINIB [INN], PIRTOBRUTINIB [JAN], Pirtobrutinib (LOXO-305)?, PIRTOBRUTINIB [WHO-DD]

Also listed as

Pirtobrutinib Chemat Brand CAS 2101700-15-4
Pirtobrutinib/ 99.76% (existing batch purity) TargetMol CAS 2101700-15-4
Pirtobrutinib 97% Ambeed CAS 2101700-15-4
5-Amino-3-[4-[[(5-fluoro-2-methoxybenzoyl)amino]methyl]phenyl]-1-[(1S)-2,2,2-trifluoro-1-methylethyl]-1H-pyrazole-4-carboxamide, 99%, 99% Chemat CAS 2101700-15-4
Pirtobrutinib, 99.90% MedChemExpress CAS 2101700-15-4