MLN8237 (Alisertib)
cas: 1028486-01-2 — see every product listed under this CAS number, including other names
MLN8237 (Alisertib) (CAS 1028486-01-2) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 1g, 200mg, 10mM (in 1ml dmso), 50mg, 500mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC12690-10 |
| cas | 1028486-01-2 |
| size | 10mg |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 802.98 Pln | |
| GLPBio | 100mg | 2450.52 Pln | |
| GLPBio | 1g | 9438.50 Pln | |
| GLPBio | 200mg | 3695.53 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 690.65 Pln | |
| GLPBio | 50mg | 1626.75 Pln | |
| GLPBio | 500mg | 6054.50 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Alisertib is an organic heterotricyclic compound that is 5H-pyrimido[5,4-d][2]benzazepine substituted by (4-carboxy-3-methoxyphenyl)amino, 2-fluoro-6-methoxyphenyl, and chloro groups at positions 2, 7 and 9, respectively. It is an aurora A kinase inhibitor (IC50 = ~1 nM). It has a role as an autophagy inducer, an antineoplastic agent, an apoptosis inducer and an Aurora kinase inhibitor. It is a monomethoxybenzene, a methoxybenzoic acid, an organic heterotricyclic compound, an organochlorine compound, a secondary amino compound and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C27H20ClFN4O4 |
|---|---|
| Molecular weight | 518.9 g/mol |
| IUPAC name | 4-[[9-chloro-7-(2-fluoro-6-methoxyphenyl)-5H-pyrimido[5,4-d][2]benzazepin-2-yl]amino]-2-methoxybenzoic acid |
| InChIKey | ZLHFILGSQDJULK-UHFFFAOYSA-N |
| SMILES | COC1=C(C(=CC=C1)F)C2=NCC3=CN=C(N=C3C4=C2C=C(C=C4)Cl)NC5=CC(=C(C=C5)C(=O)O)OC |
Computed by PubChem (NCBI)