Mertansine (Maytansinoid DM 1)

cas: 139504-50-0 — see every product listed under this CAS number, including other names

Mertansine (Maytansinoid DM 1) (CAS 139504-50-0) is a chemical reagent available from Chemat. Available pack sizes: on request. Offered by: Chemat Brand.

brandChemat Brand
catalog numberULM116023
cas139504-50-0
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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categoryChemicals
delivery timeTo be confirmed by Chemat

Mertansine is an organic heterotetracyclic compound and 19-membered macrocyclic lactam that is maytansine in which one of the hydrogens of the terminal N-acetyl group is replaced by a sulfanylmethyl group. It has a role as an antineoplastic agent and a tubulin modulator. It is a carbamate ester, a thiol, an epoxide, an organochlorine compound, an organic heterotetracyclic compound, an alpha-amino acid ester and a maytansinoid. It is functionally related to a maytansine.

Source: ChEBI

Identity
Molecular formulaC35H48ClN3O10S
Molecular weight738.3 g/mol
IUPAC name[(1S,2R,3S,5S,6S,16E,18E,20R,21S)-11-chloro-21-hydroxy-12,20-dimethoxy-2,5,9,16-tetramethyl-8,23-dioxo-4,24-dioxa-9,22-diazatetracyclo[19.3.1.110,14.03,5]hexacosa-10,12,14(26),16,18-pentaen-6-yl] (2S)-2-[methyl(3-sulfanylpropanoyl)amino]propanoate
InChIKeyANZJBCHSOXCCRQ-FKUXLPTCSA-N
SMILESC[C@@H]1[C@@H]2C[C@]([C@@H](/C=C/C=C(/CC3=CC(=C(C(=C3)OC)Cl)N(C(=O)C[C@@H]([C@]4([C@H]1O4)C)OC(=O)[C@H](C)N(C)C(=O)CCS)C)\C)OC)(NC(=O)O2)O

Computed by PubChem (NCBI)

Synonyms: Mertansine, Maytansinoid DM 1, Mertansine (DM1), maytansinoid DM1, Mertasine, N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine, N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine, L-, Maytansine, N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-, C35H48ClN3O10S, N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine

Also listed as

Mertansine GLPBio CAS 139504-50-0
DM1, 95% Combi-blocks CAS 139504-50-0
Mertansine, >95% (HPLC) TRC CAS 139504-50-0
Mertansine/ 99.76% (existing batch purity) TargetMol CAS 139504-50-0
DM1 97% Ambeed CAS 139504-50-0
N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl, )-maytansine, 25 mg Roth CAS 139504-50-0
N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl, )-maytansine, 50 mg Roth CAS 139504-50-0
N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl, )-maytansine, 100 mg Roth CAS 139504-50-0
Mertansine, 99.80% MedChemExpress CAS 139504-50-0