N-[2-(2-Pyridinyl)-6-(1,2,4,5-Tetrahydro-3H-3-Benzazepin-3-Yl)-4-Pyrimidinyl]-Β-Alanine, 99%, 99%

cas: 1373422-53-7 — see every product listed under this CAS number, including other names

N-[2-(2-Pyridinyl)-6-(1,2,4,5-Tetrahydro-3H-3-Benzazepin-3-Yl)-4-Pyrimidinyl]-Β-Alanine, 99%, 99% (CAS 1373422-53-7) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 250mg. Offered by: Chemat.

• 2D
• 3D

GSK-J1 is a monocarboxylic acid, a member of pyridines, a benzazepine, an aminopyrimidine, a secondary amino compound and a tertiary amino compound. It has a role as an EC 1.14.11.68 ([histone H3]-trimethyl-L-lysine(27) demethylase) inhibitor and an antineoplastic agent.

Source: ChEBI

Identity

Molecular formula	C22H23N5O2
Molecular weight	389.4 g/mol
IUPAC name	3-[[2-pyridin-2-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid
InChIKey	AVZCPICCWKMZDT-UHFFFAOYSA-N
SMILES	C1CN(CCC2=CC=CC=C21)C3=NC(=NC(=C3)NCCC(=O)O)C4=CC=CC=N4

Computed by PubChem (NCBI)

Synonyms: orb1222724, orb1300411, Histone demethylase inhibitor J1, s7581, 3-{[2-(pyridin-2-yl)-6-(2,

Isomers (same molecular formula)

benzyl (3S,4R)-3-ethyl-4-(1,5,7,10-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaen-12-yl)pyrrolidine-1-carboxylate C₂₂H₂₃N₅O₂

(1S,4E,7S,9R)-4-(1H-imidazol-5-ylmethylidene)-9-(2-methylbut-3-en-2-yl)-2,5,16-triazatetracyclo[7.7.0.02,7.010,15]hexadeca-10,12,14-triene-3,6-dione C₂₂H₂₃N₅O₂

N-[5-[4-(3,3-dimethylazetidine-1-carbonyl)phenyl]-[1,2,4]triazolo[1,5-a]pyridin-2-yl]cyclopropanecarboxamide C₂₂H₂₃N₅O₂

3-[[2-pyridin-3-yl-6-(1,2,4,5-tetrahydro-3-benzazepin-3-yl)pyrimidin-4-yl]amino]propanoic acid C₂₂H₂₃N₅O₂

2-[3,5-dimethyl-4-[(3-propan-2-yl-1H-pyrrolo[3,2-b]pyridin-5-yl)methyl]phenyl]-1,2,4-triazine-3,5-dione C₂₂H₂₃N₅O₂

1-[4-amino-3-(6-cyclopropyloxynaphthalen-2-yl)pyrazolo[3,4-d]pyrimidin-1-yl]-2-methylpropan-2-ol C₂₂H₂₃N₅O₂

N-(2-methoxyethyl)-3-[[4-(1-methylpyrazol-4-yl)phenyl]methyl]-2H-indazole-5-carboxamide C₂₂H₂₃N₅O₂

3-methyl-N-[2-[[(2S)-2-methylpyrrolidin-1-yl]methyl]-3H-benzimidazol-5-yl]-1,2-benzoxazole-6-carboxamide C₂₂H₂₃N₅O₂

[6-amino-4-(2-hydroxyanilino)-2-pyridinyl]-(4-phenylpiperazin-1-yl)methanone C₂₂H₂₃N₅O₂