Nirogacestat
cas: 1290543-63-3 — see every product listed under this CAS number, including other names
Nirogacestat (CAS 1290543-63-3) is a chemical reagent available from Chemat. Available pack sizes: 50mg, 25mg, 100mg. Offered by: Biosynth.
| brand | Biosynth |
|---|---|
| catalog number | QBC54363-50mg |
| cas | 1290543-63-3 |
| size | 50mg |
Need more information?
Ask us about this product — we're happy to help.
Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Biosynth | 50mg | price on request | |
| Biosynth | 25mg | price on request | |
| Biosynth | 100mg | price on request |
properties
| category | Life Sciences |
|---|---|
| purity | No data |
| delivery time | 3-4 weeks |
Nirogacestat is a member of the class of imidazoles that is 1H-imidazole substituted by a 1-[(2,2-dimethylpropyl)amino]-2-methylpropan-2-yl group at position 1 and a {N-[(2S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]-L-norvalyl}amino group at position 4. It is a gamma-secretase inhibitor whose hydrobromide salt is indicated for adult patients with progressing desmoid tumours who require systemic treatment. It has a role as an antineoplastic agent and a gamma-secretase modulator. It is a secondary carboxamide, a member of imidazoles, a member of tetralins, an organofluorine compound and a secondary amino compound. It is a conjugate base of a nirogacestat(2+).
Source: ChEBI
| Molecular formula | C27H41F2N5O |
|---|---|
| Molecular weight | 489.6 g/mol |
| IUPAC name | (2S)-2-[[(2S)-6,8-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl]amino]-N-[1-[1-(2,2-dimethylpropylamino)-2-methylpropan-2-yl]imidazol-4-yl]pentanamide |
| InChIKey | VFCRKLWBYMDAED-REWPJTCUSA-N |
| SMILES | CCC[C@@H](C(=O)NC1=CN(C=N1)C(C)(C)CNCC(C)(C)C)N[C@H]2CCC3=C(C2)C(=CC(=C3)F)F |
Computed by PubChem (NCBI)
