Pexidartinib 98%
cas: 1029044-16-3 — see every product listed under this CAS number, including other names
Pexidartinib 98% (CAS 1029044-16-3) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 50mg, 100mg, 250mg, 1g, 5g. Offered by: Ambeed.
| brand | Ambeed |
|---|---|
| catalog number | A392608-1mg |
| cas | 1029044-16-3 |
| size | 1mg |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Ambeed | 1mg | 142.31 Pln | |
| Ambeed | 5mg | 220.19 Pln | |
| Ambeed | 50mg | 503.88 Pln | |
| Ambeed | 100mg | 804.25 Pln | |
| Ambeed | 250mg | 1354.94 Pln | |
| Ambeed | 1g | 2884.62 Pln | |
| Ambeed | 5g | 9910.06 Pln |
properties
| purity | 98% |
|---|---|
| delivery time | 1-2 weeks |
| ambeed catalog no. | A392608 |
Pexidartinib is a pyrrolopyridine that is 5-chloro-1H-pyrrolo[2,3-b]pyridine which is substituted by a [6-({[6-(trifluoromethyl)pyridin-3-yl]methyl}amino)pyridin-3-yl]methyl group at position 3. It is a potent multi-targeted receptor tyrosine kinase inhibitor of CSF-1R, KIT, and FLT3 (IC50 of 20 nM, 10 nM and 160 nM, respectively). Approved by the FDA for the treatment of adult patients with symptomatic tenosynovial giant cell tumor (TGCT). It has a role as an antineoplastic agent and an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor. It is an organochlorine compound, an organofluorine compound, an aminopyridine, a pyrrolopyridine and a secondary amino compound.
Source: ChEBI
| Molecular formula | C20H15ClF3N5 |
|---|---|
| Molecular weight | 417.8 g/mol |
| IUPAC name | 5-[(5-chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)methyl]-N-[[6-(trifluoromethyl)-3-pyridinyl]methyl]pyridin-2-amine |
| InChIKey | JGWRKYUXBBNENE-UHFFFAOYSA-N |
| SMILES | C1=CC(=NC=C1CC2=CNC3=C2C=C(C=N3)Cl)NCC4=CN=C(C=C4)C(F)(F)F |
Computed by PubChem (NCBI)