Praliciguat
cas: 1628730-49-3 — see every product listed under this CAS number, including other names
Praliciguat (CAS 1628730-49-3) is a chemical reagent available from Chemat. Available pack sizes: on request, 10mg, 10mM (in 1ml dmso), 5mg, 50mg, 1mg, 2mg, 25mg. Offered by: Chemat Brand, GLPBio, Biosynth.
| brand | Chemat Brand |
|---|---|
| catalog number | ULP326001 |
| cas | 1628730-49-3 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| GLPBio | 10mg | 3447.46 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 2731.35 Pln | |
| GLPBio | 5mg | 2394.35 Pln | |
| GLPBio | 50mg | 7786.29 Pln | |
| Biosynth | 10mg | price on request | |
| Biosynth | 1mg | price on request | |
| Biosynth | 2mg | price on request | |
| Biosynth | 5mg | price on request | |
| Biosynth | 25mg | price on request |
properties
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
Praliciguat is a member of the class of pyrazoles that is 5-fluoro-2-(1H-pyrazol-3-yl)pyrimidine which is substituted by a 2-fluorobenzyl group at position 1, 1,2-oxazol-3-yl group at position 5, and by a [3,3,3-trifluoro-2-hydroxy-2-(trifluoromethyl)propyl]nitrilo group at position 4. It is a soluble guanylate cyclase stimulator under clinical development for the treatment of heart failure with preserved ejection fraction. It has a role as a vasodilator agent, an antihypertensive agent, an anti-inflammatory agent and a soluble guanylate cyclase activator. It is a member of pyrazoles, a tertiary alcohol, an organofluorine compound, an aminopyrimidine, a secondary amino compound, a member of isoxazoles and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C21H14F8N6O2 |
|---|---|
| Molecular weight | 534.4 g/mol |
| IUPAC name | 1,1,1,3,3,3-hexafluoro-2-[[[5-fluoro-2-[1-[(2-fluorophenyl)methyl]-5-(1,2-oxazol-3-yl)pyrazol-3-yl]pyrimidin-4-yl]amino]methyl]propan-2-ol |
| InChIKey | CYSJNTQNMDWAJV-UHFFFAOYSA-N |
| SMILES | C1=CC=C(C(=C1)CN2C(=CC(=N2)C3=NC=C(C(=N3)NCC(C(F)(F)F)(C(F)(F)F)O)F)C4=NOC=C4)F |
Computed by PubChem (NCBI)