cas: 283173-50-2 — see every product listed under this CAS number, including other names
Rucaparib (free base) (CAS 283173-50-2) is a chemical reagent available from Chemat. Available pack sizes: 50mg, 10mg, 200mg, 5mg, 10mM (in 1ml dmso). Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC13249-50 |
| cas | 283173-50-2 |
| size | 50mg |
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| brand | size | price | |
|---|---|---|---|
| GLPBio | 50mg | 1622.07 Pln | |
| GLPBio | 10mg | 877.87 Pln | |
| GLPBio | 200mg | 3152.59 Pln | |
| GLPBio | 5mg | 662.57 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 690.65 Pln |
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Rucaparib is a member of the class of azepinoindoles that is 1,3,4,5-tetrahydro-6H-azepino[5,4,3-cd]indol-6-one carrying additional 4-[(methylamino)methyl]phenyl and fluoro substituents at positions 2 and 8 respectively. It is an inhibitor of poly (ADP-ribose) polymerase and is used (as the camsylate salt) as monotherapy for advanced ovarian cancer and deleterious germline or somatic BRCA mutation. It has a role as an antineoplastic agent and an EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor. It is an azepinoindole, a member of caprolactams, an organofluorine compound and a secondary amino compound. It is a conjugate base of a rucaparib(1+).
Source: ChEBI
| Molecular formula | C19H18FN3O |
|---|---|
| Molecular weight | 323.4 g/mol |
| IUPAC name | 6-fluoro-2-[4-(methylaminomethyl)phenyl]-3,10-diazatricyclo[6.4.1.04,13]trideca-1,4,6,8(13)-tetraen-9-one |
| InChIKey | HMABYWSNWIZPAG-UHFFFAOYSA-N |
| SMILES | CNCC1=CC=C(C=C1)C2=C3CCNC(=O)C4=C3C(=CC(=C4)F)N2 |
Computed by PubChem (NCBI)