cas: 922150-11-6 — see every product listed under this CAS number, including other names
SCH 529074, 98%, 98% (CAS 922150-11-6) is a chemical reagent available from Chemat. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch12ENFH-5mg |
| cas | 922150-11-6 |
| size | 5mg |
| availability | 0.2g |
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| brand | size | price | |
|---|---|---|---|
| Chemat | 5mg | 645.20 Pln | |
| Chemat | 10mg | 1134.80 Pln | |
| Chemat | 25mg | 2507.60 Pln | |
| Chemat | 50mg | 4019.60 Pln | |
| Chemat | 100mg | 6741.20 Pln |
| purity | 98% |
|---|---|
| delivery time | 3 weeks |
SCH529074 is a potent and orally active p53 activator. SCH529074 binds specifically and conformation-dependently to p53 DBD ( DNA binding domain) with a Ki of 1-2 uM in a saturable manner. SCH529074 restores mutant p53 function and interrupts HDM2-mediated ubiquitination of wild Type p53. SCH529074 can be used for the study of non-small-cell lung carcinoma (NSCLC). (MedChemExpress).
Source: ChEBI
| Molecular formula | C31H36Cl2N6 |
|---|---|
| Molecular weight | 563.6 g/mol |
| IUPAC name | N-[2-[[4-[bis(4-chlorophenyl)methyl]piperazin-1-yl]methyl]quinazolin-4-yl]-N',N'-dimethylpropane-1,3-diamine |
| InChIKey | NCAJLQDPTZBGJV-UHFFFAOYSA-N |
| SMILES | CN(C)CCCNC1=NC(=NC2=CC=CC=C21)CN3CCN(CC3)C(C4=CC=C(C=C4)Cl)C5=CC=C(C=C5)Cl |
Computed by PubChem (NCBI)