Suramin
cas: 145-63-1 — see every product listed under this CAS number, including other names
Suramin (CAS 145-63-1) is a chemical reagent available from Chemat. Available pack sizes: 2g, 1g, 5g, Get quote. Offered by: Biosynth, MedChemExpress.
| brand | Biosynth |
|---|---|
| catalog number | AAA14563-2g |
| cas | 145-63-1 |
| size | 2g |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Biosynth | 2g | price on request | |
| Biosynth | 1g | price on request | |
| Biosynth | 5g | price on request | |
| MedChemExpress | Get quote | price on request |
properties
| category | Life Sciences |
|---|---|
| purity | No data |
| delivery time | 3-4 Weeks |
Suramin is a member of the class of phenylureas that is urea in which each of the amino groups has been substituted by a 3-({2-methyl-5-[(4,6,8-trisulfo-1-naphthyl)carbamoyl]phenyl}carbamoyl)phenyl group. An activator of both the rabbit skeletal muscle RyR1 and sheep cardiac RyR2 isoform ryanodine receptor channels, it has been used for the treatment of human African trypanosomiasis for over 100 years. It has a role as an antinematodal drug, an antineoplastic agent, a trypanocidal drug, an EC 2.7.11.13 (protein kinase C) inhibitor, a GABA-gated chloride channel antagonist, an angiogenesis inhibitor, a GABA antagonist, a ryanodine receptor agonist, an apoptosis inhibitor and a purinergic receptor P2 antagonist. It is a member of phenylureas, a secondary carboxamide and a naphthalenesulfonic acid. It is functionally related to a naphthalene-1,3,5-trisulfonic acid. It is a conjugate acid of a suramin(6-).
Source: ChEBI
| Molecular formula | C51H40N6O23S6 |
|---|---|
| Molecular weight | 1297.3 g/mol |
| IUPAC name | 8-[[4-methyl-3-[[3-[[3-[[2-methyl-5-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl]carbamoyl]phenyl]carbamoylamino]benzoyl]amino]benzoyl]amino]naphthalene-1,3,5-trisulfonic acid |
| InChIKey | FIAFUQMPZJWCLV-UHFFFAOYSA-N |
| SMILES | CC1=C(C=C(C=C1)C(=O)NC2=C3C(=CC(=CC3=C(C=C2)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)NC(=O)C4=CC(=CC=C4)NC(=O)NC5=CC=CC(=C5)C(=O)NC6=C(C=CC(=C6)C(=O)NC7=C8C(=CC(=CC8=C(C=C7)S(=O)(=O)O)S(=O)(=O)O)S(=O)(=O)O)C |
Computed by PubChem (NCBI)
Synonyms:
suramin, Suramine, Fourneau, Farma, Belganyl, Metaret, Monosodium Salt Suramin, Salt Suramin, Monosodium, Naganol, Naphuride