cas: 309913-83-5 — see every product listed under this CAS number, including other names
Talmapimod (CAS 309913-83-5) is a chemical reagent available from Chemat. Available pack sizes: on request. Offered by: Chemat Brand.
| brand | Chemat Brand |
|---|---|
| catalog number | ULT410001 |
| cas | 309913-83-5 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request |
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
Talmapimod is an indolecarboxamide obtained by formal condensation of the carboxy group of 6-chloro-3-[(dimethylamino)(oxo)acetyl]-1-methylindole-5-carboxylic acid with the secondary amino group of (2S,5R)-1-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine. It is a potent inhibitor of MAPK and exhibits anti-cancer properties. It has a role as an antineoplastic agent, an apoptosis inducer and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is a dicarboxylic acid diamide, a N-acylpiperazine, a N-alkylpiperazine, an indolecarboxamide, a chloroindole, an aromatic amide, an aromatic ketone and a member of monofluorobenzenes.
Source: ChEBI
| Molecular formula | C27H30ClFN4O3 |
|---|---|
| Molecular weight | 513.0 g/mol |
| IUPAC name | 2-[6-chloro-5-[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine-1-carbonyl]-1-methylindol-3-yl]-N,N-dimethyl-2-oxoacetamide |
| InChIKey | ZMELOYOKMZBMRB-DLBZAZTESA-N |
| SMILES | C[C@@H]1CN([C@H](CN1C(=O)C2=C(C=C3C(=C2)C(=CN3C)C(=O)C(=O)N(C)C)Cl)C)CC4=CC=C(C=C4)F |
Computed by PubChem (NCBI)