cas: 475108-18-0 — see every product listed under this CAS number, including other names
Tivozanib (Standard) (CAS 475108-18-0) is a chemical reagent available from Chemat. Available pack sizes: 5 mg, 50 mg, 10 mg, 100 mg, 25 mg. Offered by: MedChemExpress.
| brand | MedChemExpress |
|---|---|
| catalog number | HY-10977R-5 mg |
| cas | 475108-18-0 |
| size | 5 mg |
| availability | Get quote |
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| brand | size | price | |
|---|---|---|---|
| MedChemExpress | 5 mg | 960.56 Pln | |
| MedChemExpress | 50 mg | 4420.34 Pln | |
| MedChemExpress | 10 mg | 1462.12 Pln | |
| MedChemExpress | 100 mg | 6835.22 Pln | |
| MedChemExpress | 25 mg | 2808.88 Pln |
| delivery time | over 3 weeks |
|---|---|
| purity | no data |
Tivozanib is a member of the class of quinolines that is 6,7-dimethoxyquinoline substituted by a 3-chloro-4-{[(5-methyl-1,2-oxazol-3-yl)carbamoyl]amino}phenoxy group at position 4. It is a potent and selective inhibitor of VEGF receptor tyrosine kinases and was previously in clinical development for the treatment of metastatic renal cell carcinoma. It has a role as an antineoplastic agent, a vascular endothelial growth factor receptor antagonist and an apoptosis inducer. It is a member of phenylureas, a member of quinolines, an aromatic ether, a member of isoxazoles and a member of monochlorobenzenes.
Source: ChEBI
| Molecular formula | C22H19ClN4O5 |
|---|---|
| Molecular weight | 454.9 g/mol |
| IUPAC name | 1-[2-chloro-4-(6,7-dimethoxyquinolin-4-yl)oxyphenyl]-3-(5-methyl-1,2-oxazol-3-yl)urea |
| InChIKey | SPMVMDHWKHCIDT-UHFFFAOYSA-N |
| SMILES | CC1=CC(=NO1)NC(=O)NC2=C(C=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)OC)Cl |
Computed by PubChem (NCBI)