Topotecan
cas: 123948-87-8 — see every product listed under this CAS number, including other names
Topotecan (CAS 123948-87-8) is a chemical reagent available from Chemat. Available pack sizes: on request, 10mg, 100mg, 1000mg, 10mM (in 1ml dmso), 50mg, Get quote. Offered by: Chemat Brand, GLPBio, MedChemExpress.
| brand | Chemat Brand |
|---|---|
| catalog number | ULT261 |
| cas | 123948-87-8 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| GLPBio | 10mg | 550.23 Pln | |
| GLPBio | 100mg | 901.27 Pln | |
| GLPBio | 1000mg | 4271.23 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 583.00 Pln | |
| GLPBio | 50mg | 877.87 Pln | |
| MedChemExpress | Get quote | price on request |
properties
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
Topotecan is a pyranoindolizinoquinoline used as an antineoplastic agent. It is a derivative of camptothecin and works by binding to the topoisomerase I-DNA complex and preventing religation of these 328 single strand breaks. It has a role as an antineoplastic agent and an EC 5.99.1.2 (DNA topoisomerase) inhibitor.
Source: ChEBI
| Molecular formula | C23H23N3O5 |
|---|---|
| Molecular weight | 421.4 g/mol |
| IUPAC name | (19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione |
| InChIKey | UCFGDBYHRUNTLO-QHCPKHFHSA-N |
| SMILES | CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O |
Computed by PubChem (NCBI)
Synonyms:
topotecan, Hycamptamine, Topotecan lactone, Nogitecan, Hycamptin, Topotecane, (S)-Topotecan, Topotecanum, Topophore C, TopoCED