Vorapaxar

cas: 618385-01-6 — see every product listed under this CAS number, including other names

Vorapaxar (CAS 618385-01-6) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 25mg, 5mg, 10mM (in 1ml dmso), 50mg, 100mg. Offered by: GLPBio, Biosynth, Sigma-Aldrich.

brandGLPBio
catalog numberGC17545-10
cas618385-01-6
size10mg
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Available pack sizes

brand size price
GLPBio 10mg 1453.57 Pln
GLPBio 25mg 2586.25 Pln
GLPBio 5mg 980.84 Pln
GLPBio 10mM (in 1ml dmso) 1107.21 Pln
GLPBio 50mg 3236.84 Pln
Biosynth 10mg price on request
Biosynth 5mg price on request
Biosynth 25mg price on request
Biosynth 100mg price on request
Biosynth 50mg price on request
Sigma-Aldrich 25MG 1860.00 Pln
Sigma-Aldrich 5MG 500.00 Pln

properties

purityNo data
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Vorapaxar is a carbamate ester that is the ethyl ester of [(1R,3aR,4aR,6R,8aR,9S,9aS)-9-{(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethynyl}-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl]carbamic acid. A protease-activated receptor-1 antagonist used (as its sulfate salt) for the reduction of thrombotic cardiovascular events in patients with a history of myocardial infarction (MI) or with peripheral arterial disease. It has been shown to reduce the rate of a combined endpoint of cardiovascular death, MI, stroke and urgent coronary revascularisation. It has a role as a cardiovascular drug, a platelet aggregation inhibitor and a protease-activated receptor-1 antagonist. It is a carbamate ester, a lactone, a member of pyridines, an organofluorine compound and a naphthofuran. It is a conjugate base of a vorapaxar(1+).

Source: ChEBI

Identity
Molecular formulaC29H33FN2O4
Molecular weight492.6 g/mol
IUPAC nameethyl N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]-1-methyl-3-oxo-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-1H-benzo[f][2]benzofuran-6-yl]carbamate
InChIKeyZBGXUVOIWDMMJE-QHNZEKIYSA-N
SMILESCCOC(=O)N[C@@H]1CC[C@@H]2[C@@H](C1)C[C@@H]3[C@H]([C@H]2/C=C/C4=NC=C(C=C4)C5=CC(=CC=C5)F)[C@H](OC3=O)C

Computed by PubChem (NCBI)

Synonyms: Vorapaxar, vorapaxarum, Vorapaxar free base, Vorapaxar [USAN], Vorapaxar (MK-5348), Vorapaxar [USAN:INN], Vorapaxar?, Vorapaxar [INN], an-6-yl]carbamate, 618385-01-6 (free base)
Related forms of this compound
ethyl N-[(1R,3aR,4aR,6S,8aR,9S,9aS)-9-[(E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]-1-methyl-3-oxo-3a,4,4a,5,6,7,8,8a,9,9a-decahydro-1H-benzo[f][2]benzofuran-6-yl]carbamate C29H33FN2O4

Also listed as

Vorapaxar/ 99.93% (existing batch purity) TargetMol CAS 618385-01-6
Vorapaxar, 99.85% MedChemExpress CAS 618385-01-6
Vorapaxar (Standard) MedChemExpress CAS 618385-01-6
Vorapaxar, 98% Ambeed CAS 618385-01-6
Ethyl ((1R,3aR,4aR,6R,8aR,9S,9aS)-9-((E)-2-(5-(3-fluorophenyl)pyridin-2-yl)vinyl)-1-methyl-3-oxododecahydronaphtho[2,3-c]furan-6-yl)carbamate, 98% BLDpharm CAS 618385-01-6
Carbamic acid, N-[(1R,3aR,4aR,6R,8aR,9S,9aS)-9-[(1E)-2-[5-(3-fluorophenyl)-2-pyridinyl]ethenyl]dodecahydro-1-methyl-3-oxonaphtho[2,3-c]furan-6-yl]-, ethyl ester, 98% Chemat CAS 618385-01-6