Vx-745 >= 98 % HPLC

cas: 209410-46-8 — see every product listed under this CAS number, including other names

Vx-745 >= 98 % HPLC (CAS 209410-46-8) is a chemical reagent available from Chemat. Available pack sizes: 25MG, 5MG. Offered by: Sigma-Aldrich.

brandSigma-Aldrich
catalog numberSML1638-25MG
cas209410-46-8
size25MG
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Available pack sizes

brand size price
Sigma-Aldrich 25MG 2010.00 Pln
Sigma-Aldrich 5MG 536.00 Pln
Structural formula: {0} (CAS {1})

VX-745 is a member of the class of pyrimidopyridazines that is 6H-pyrimido[1,6-b]pyridazin-6-one substituted at positions 2 and 5 by (2,4-difluorophenyl)sulfanyl and 2,6-dichlorophenyl groups respectively. It has a role as an anti-inflammatory drug, an apoptosis inducer and an EC 2.7.11.24 (mitogen-activated protein kinase) inhibitor. It is a dichlorobenzene, an aryl sulfide, a difluorobenzene and a pyrimidopyridazine.

Source: ChEBI

Identity
Molecular formulaC19H9Cl2F2N3OS
Molecular weight436.3 g/mol
IUPAC name5-(2,6-dichlorophenyl)-2-(2,4-difluorophenyl)sulfanylpyrimido[1,6-b]pyridazin-6-one
InChIKeyVEPKQEUBKLEPRA-UHFFFAOYSA-N
SMILESC1=CC(=C(C(=C1)Cl)C2=C3C=CC(=NN3C=NC2=O)SC4=C(C=C(C=C4)F)F)Cl

Computed by PubChem (NCBI)

Synonyms: Neflamapimod, neflamapimodum, 6H-pyrimido(1,6-b)pyridazin-6-one,5-(2,6-dichlorophenyl)-2-(phenylthio)-, C19H9Cl2F2N3OS, Neflamapimod [USAN], Kinome_3767, s1458, Neflamapimod (USAN/INN), NEFLAMAPIMOD [INN], NEFLAMAPIMOD [WHO-DD]

Also listed as

VX 745 TRC CAS 209410-46-8
Neflamapimod/ 99.02% (existing batch purity) TargetMol CAS 209410-46-8
VX–745 GLPBio CAS 209410-46-8
Neflamapimod Biosynth CAS 209410-46-8
VX-745 Chemat CAS 209410-46-8
Neflamapimod, 99.32% MedChemExpress CAS 209410-46-8
Neflamapimod, 98% Ambeed CAS 209410-46-8
5-(2,6-Dichlorophenyl)-2-[(2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one, 98% Chemat CAS 209410-46-8
5-(2,6-Dichlorophenyl)-2-((2,4-difluorophenyl)thio)-6H-pyrimido[1,6-b]pyridazin-6-one, 98% Fluorochem CAS 209410-46-8