iFSP1
cas: 150651-39-1 — see every product listed under this CAS number, including other names
iFSP1 (CAS 150651-39-1) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 5mg, 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC45928-10 |
| cas | 150651-39-1 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 615.76 Pln | |
| GLPBio | 100mg | 2099.48 Pln | |
| GLPBio | 5mg | 522.15 Pln | |
| GLPBio | 50mg | 1313.16 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
IFSP1 is a member of the class of pyridobenzimidazoles that is pyrido[1,2-a]benzimidazole substituted by amino, cyano, 4-methylphenyl, and cyano groups at positions 1, 2, 3 and 4, respectively. It is a potent inhibitor of ferroptosis suppressor protein 1 (FSP1) with EC50 of 103 nM. It induces ferroptosis in GPX4 knockout cells that overexpress FSP1. It has a role as a ferroptosis inducer, a ferroptosis suppressor protein 1 inhibitor and an antineoplastic agent. It is a pyridobenzimidazole, a nitrile, a member of toluenes, an aromatic amine and a primary amino compound.
Source: ChEBI
| Molecular formula | C20H13N5 |
|---|---|
| Molecular weight | 323.3 g/mol |
| IUPAC name | 1-amino-3-(4-methylphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile |
| InChIKey | FNESYDFRCQEEKA-UHFFFAOYSA-N |
| SMILES | CC1=CC=C(C=C1)C2=C(C3=NC4=CC=CC=C4N3C(=C2C#N)N)C#N |
Computed by PubChem (NCBI)
Synonyms:
iFSP1, 1-Amino-3-p-tolyl-benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile, 1-amino-3-(4-methylphenyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile, Oprea1_094186, 1-amino-3-(p-tolyl)benzo[4,5]imidazo[1,2-a]pyridine-2,4-dicarbonitrile, 1-Amino-3-(4-methylphenyl)-pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile, 1-amino-3-(p-tolyl)pyrido[1,2-a]benzimidazole-2,4-dicarbonitrile, iFSP 1, iFSP-1, iFSP1?