Products 14913-33-8
CAS 14913-33-8 appears in our catalog under these names: Cisplatinum EP Impurity A (Transplatin), Transplatin, trans–Platinum diammine dichloride, trans-Dichlorodiamine platinum(II)/ 99.95% (metals basis), trans-Diamminedichloroplatinum(II), Pt 64.5% min . Offered by: Chemat Brand, TRC, GLPBio, Chemat, Thermo Scientific (Alfa Aesar). Available pack sizes: on request, 100mg, 10mg, 250mg, 1g, 5g, 0.25g , 0,5g.
Cisplatin is a diamminedichloroplatinum compound in which the two ammine ligands and two chloro ligands are oriented in a cis planar configuration around the central platinum ion. An anticancer drug that interacts with, and forms cross-links between, DNA and proteins, it is used as a neoplasm inhibitor to treat solid tumours, primarily of the testis and ovary. Commonly but incorrectly described as an alkylating agent due to its mechanism of action (but it lacks alkyl groups). It has a role as a ferroptosis inducer, a mutagen, an antineoplastic agent, a photosensitizing agent, a cross-linking reagent, a genotoxin, a nephrotoxic agent and an apoptosis inducer.
Source: ChEBI
| Molecular formula | Cl2H6N2Pt+2 |
|---|---|
| Molecular weight | 300.05 g/mol |
| IUPAC name | azane;dichloroplatinum(2+) |
| InChIKey | BSJGASKRWFKGMV-UHFFFAOYSA-L |
| SMILES | N.N.Cl[Pt+2]Cl |
Computed by PubChem (NCBI)
Synonyms:
trans-platin, trans-Platinum(II) diamminedichloride, (SP-4-1)-diamminedichloroplatinum, trans-diamminedichloridoplatinum(II), (SP-4-1)-diamminedichloridoplatinum, transDDP, trans-diamminedichloroplatinum II, trans-dichlorodiammineplatinum II, transDichlorodiammine platinum, transPlatinumdiammine dichloride