(+)–Aphidicolin
cas: 38966-21-1 — see every product listed under this CAS number, including other names
(+)–Aphidicolin (CAS 38966-21-1) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 25mg, 5mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC10867-1 |
| cas | 38966-21-1 |
| size | 1mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 1mg | 980.84 Pln | |
| GLPBio | 25mg | 6648.93 Pln | |
| GLPBio | 5mg | 2216.49 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Aphidicolin is a tetracyclic diterpenoid that has an tetradecahydro-8,11a-methanocyclohepta[a]naphthalene skeleton with two hydroxymethyl substituents at positions 4 and 9, two methyl substituents at positions 4 and 11b and two hydroxy substituents at positions 3 and 9. An antibiotic with antiviral and antimitotical properties. Aphidicolin is a reversible inhibitor of eukaryotic nuclear DNA replication. It has a role as an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor, an antimicrobial agent, an antineoplastic agent, an antiviral drug, a DNA synthesis inhibitor, an antimitotic, an apoptosis inducer, a fungal metabolite and an Aspergillus metabolite.
Source: ChEBI
| Molecular formula | C20H34O4 |
|---|---|
| Molecular weight | 338.5 g/mol |
| IUPAC name | (1S,2S,5R,6R,7R,10S,12R,13R)-6,13-bis(hydroxymethyl)-2,6-dimethyltetracyclo[10.3.1.01,10.02,7]hexadecane-5,13-diol |
| InChIKey | NOFOAYPPHIUXJR-APNQCZIXSA-N |
| SMILES | C[C@]12CC[C@H]([C@@]([C@@H]1CC[C@@H]3[C@@]24CC[C@@]([C@H](C3)C4)(CO)O)(C)CO)O |
Computed by PubChem (NCBI)