Products 38966-21-1
CAS 38966-21-1 appears in our catalog under these names: (+)–Aphidicolin, (+)-Aphidicolin, >95% (HPLC), Aphidicolin, Aphidicolin , Aphidicolin, 98.00%. Offered by: GLPBio, TRC, TargetMol, Thermo Scientific (Alfa Aesar), Biosynth. Available pack sizes: 1mg, 10mg, 5mg, 25mg, 0,5mg, 2mg, 1ML, Get quote.
Aphidicolin is a tetracyclic diterpenoid that has an tetradecahydro-8,11a-methanocyclohepta[a]naphthalene skeleton with two hydroxymethyl substituents at positions 4 and 9, two methyl substituents at positions 4 and 11b and two hydroxy substituents at positions 3 and 9. An antibiotic with antiviral and antimitotical properties. Aphidicolin is a reversible inhibitor of eukaryotic nuclear DNA replication. It has a role as an EC 2.7.7.7 (DNA-directed DNA polymerase) inhibitor, an antimicrobial agent, an antineoplastic agent, an antiviral drug, a DNA synthesis inhibitor, an antimitotic, an apoptosis inducer, a fungal metabolite and an Aspergillus metabolite.
Source: ChEBI
| Molecular formula | C20H34O4 |
|---|---|
| Molecular weight | 338.5 g/mol |
| IUPAC name | (1S,2S,5R,6R,7R,10S,12R,13R)-6,13-bis(hydroxymethyl)-2,6-dimethyltetracyclo[10.3.1.01,10.02,7]hexadecane-5,13-diol |
| InChIKey | NOFOAYPPHIUXJR-APNQCZIXSA-N |
| SMILES | C[C@]12CC[C@H]([C@@]([C@@H]1CC[C@@H]3[C@@]24CC[C@@]([C@H](C3)C4)(CO)O)(C)CO)O |
Computed by PubChem (NCBI)