(+)-JQ 1

cas: 1268524-70-4 — see every product listed under this CAS number, including other names

(+)-JQ 1 (CAS 1268524-70-4) is a chemical reagent available from Chemat. Available pack sizes: 50mg, 10mg, 250mg, 500mg, 1000mg. Offered by: Biosynth.

brandBiosynth
catalog numberFC43273-50mg
cas1268524-70-4
size50mg
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
Biosynth 50mg price on request
Biosynth 10mg price on request
Biosynth 250mg price on request
Biosynth 500mg price on request
Biosynth 1000mg price on request

properties

categoryControlled Products
purityNo data
delivery time1-2 weeks
Structural formula: {0} (CAS {1})

JQ1 is a member of the class of thienotriazolodiazepines that is the tert-butyl ester of [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid. An inhibitor of bromodomain-containing protein 4 that exhibits anti-cancer and cardioprotective properties. It has a role as a bromodomain-containing protein 4 inhibitor, a ferroptosis inducer, an antineoplastic agent, an angiogenesis inhibitor, an anti-inflammatory agent, an apoptosis inducer and a cardioprotective agent. It is a tert-butyl ester, a carboxylic ester, an organochlorine compound and a thienotriazolodiazepine.

Source: ChEBI

Identity
Molecular formulaC23H25ClN4O2S
Molecular weight457.0 g/mol
IUPAC nametert-butyl 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate
InChIKeyDNVXATUJJDPFDM-KRWDZBQOSA-N
SMILESCC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C

Computed by PubChem (NCBI)

Synonyms: C23H25ClN4O2S, 3mxf, 4flp, 4qzs, orb1226633, orb1306457, DNVXATUJJDPFDM-KRWDZBQOSA-N
Related forms of this compound
tert-butyl 2-[7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate C23H25ClN4O2S
tert-butyl 2-[(9R)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate C23H25ClN4O2S

Also listed as

(+)-JQ-1, 98% Combi-blocks CAS 1268524-70-4
(+)-JQ1 Chemat Brand CAS 1268524-70-4
(S)-(+)-Tert-butyl 2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate, >95% (HPLC) TRC CAS 1268524-70-4
(+)-JQ-1/ 98% TargetMol CAS 1268524-70-4
Bromodomain Inhibitor, (+)–JQ1 GLPBio CAS 1268524-70-4
(+)-JQ1 98% Ambeed CAS 1268524-70-4
(S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate, 98%, 98% Chemat CAS 1268524-70-4
(+)-JQ-1, 99.90% MedChemExpress CAS 1268524-70-4