Products 1268524-70-4

CAS 1268524-70-4 appears in our catalog under these names: (+)-JQ-1, 98%, (+)-JQ1, (S)-(+)-Tert-butyl 2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate, >95% (HPLC), (+)-JQ-1/ 98%, Bromodomain Inhibitor, (+)–JQ1. Offered by: Combi-blocks, Chemat Brand, TRC, TargetMol, GLPBio. Available pack sizes: 1g, 5g, 250mg, on request, 100mg, 25mg, 5mg, 1mg.

(+)-JQ-1, 98%
Combi-blocks
  • size: 1g, 5g, 250mg
  • Variants: 3
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(+)-JQ1
Chemat Brand, Chemat
  • size: on request, 10mg, 1mg, 5mg
  • Variants: 4
from 1480.19
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(S)-(+)-Tert-butyl 2-(4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepin-6-yl)acetate, >95% (HPLC)
TRC
  • size: 100mg, 25mg, 5mg
  • Variants: 3
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(+)-JQ-1/ 98%
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 9
from 386.15
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Bromodomain Inhibitor, (+)–JQ1
GLPBio
  • size: 1mg, 10mg, 5mg, 10mM (in 1ml dmso)
  • Variants: 5
from 583.00
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(+)-JQ 1
Biosynth
  • size: 50mg, 10mg, 250mg, 500mg
  • Variants: 5
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(+)-JQ1 98%
Ambeed
  • size: 1mg, 10mg, 25mg, 50mg
  • Variants: 8
from 125.62
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(S)-(+)-Tert-butyl 2-(4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)acetate, 98%, 98%
Chemat
  • size: 10mg, 25mg, 50mg, 100mg
  • Variants: 10
from 88.40
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(+)-JQ-1, 99.90%
MedChemExpress
  • size: 10mM/1mL, 10 mg, 50 mg, 100 mg
  • Variants: 7
from 361.49
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Structural formula: {0} (CAS {1})

JQ1 is a member of the class of thienotriazolodiazepines that is the tert-butyl ester of [(6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl]acetic acid. An inhibitor of bromodomain-containing protein 4 that exhibits anti-cancer and cardioprotective properties. It has a role as a bromodomain-containing protein 4 inhibitor, a ferroptosis inducer, an antineoplastic agent, an angiogenesis inhibitor, an anti-inflammatory agent, an apoptosis inducer and a cardioprotective agent. It is a tert-butyl ester, a carboxylic ester, an organochlorine compound and a thienotriazolodiazepine.

Source: ChEBI

Identity
Molecular formulaC23H25ClN4O2S
Molecular weight457.0 g/mol
IUPAC nametert-butyl 2-[(9S)-7-(4-chlorophenyl)-4,5,13-trimethyl-3-thia-1,8,11,12-tetrazatricyclo[8.3.0.02,6]trideca-2(6),4,7,10,12-pentaen-9-yl]acetate
InChIKeyDNVXATUJJDPFDM-KRWDZBQOSA-N
SMILESCC1=C(SC2=C1C(=N[C@H](C3=NN=C(N32)C)CC(=O)OC(C)(C)C)C4=CC=C(C=C4)Cl)C

Computed by PubChem (NCBI)

Synonyms: C23H25ClN4O2S, 3mxf, 4flp, 4qzs, orb1226633, orb1306457, DNVXATUJJDPFDM-KRWDZBQOSA-N