1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide, 99%

cas: 1152311-62-0 — see every product listed under this CAS number, including other names

1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide, 99% (CAS 1152311-62-0) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 100mg, 250mg, 1g, 5g. Offered by: Chemat.

• 2D
• 3D

Tezacaftor is a CFTR (cystic fibrosis transmembrane conductance regulator) corrector used to treat cystic fibrosis in patients with susceptible mutations.

Source: ChEBI

Identity

Molecular formula	C26H27F3N2O6
Molecular weight	520.5 g/mol
IUPAC name	1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide
InChIKey	MJUVRTYWUMPBTR-MRXNPFEDSA-N
SMILES	CC(C)(CO)C1=CC2=CC(=C(C=C2N1C[C@H](CO)O)F)NC(=O)C3(CC3)C4=CC5=C(C=C4)OC(O5)(F)F

Computed by PubChem (NCBI)

Synonyms: Tezacaftor, TRIKAFTA COMPONENT TEZACAFTOR, SYMKEVI COMPONENT TEZACAFTOR, tezacaftorum, Tezacaftor (VX-661), Tezacaftor [USAN], Alyftrek, Kaftrio, Symdeko, Tezacaftor; VX-661

Related forms of this compound

2,2,3,3-tetradeuterio-1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide C₂₆H₂₇F₃N₂O₆

1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide C₂₆H₂₇F₃N₂O₆