Tezacaftor (VX-661)

cas: 1152311-62-0 — see every product listed under this CAS number, including other names

Tezacaftor (VX-661) (CAS 1152311-62-0) is a chemical reagent available from Chemat. Available pack sizes: on request. Offered by: Chemat Brand.

brandChemat Brand
catalog numberULT303001
cas1152311-62-0
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
Need more information?

Ask us about this product — we're happy to help.

Available pack sizes

brand size price
Chemat Brand on request price on request

properties

purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Tezacaftor is a CFTR (cystic fibrosis transmembrane conductance regulator) corrector used to treat cystic fibrosis in patients with susceptible mutations.

Source: ChEBI

Identity
Molecular formulaC26H27F3N2O6
Molecular weight520.5 g/mol
IUPAC name1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide
InChIKeyMJUVRTYWUMPBTR-MRXNPFEDSA-N
SMILESCC(C)(CO)C1=CC2=CC(=C(C=C2N1C[C@H](CO)O)F)NC(=O)C3(CC3)C4=CC5=C(C=C4)OC(O5)(F)F

Computed by PubChem (NCBI)

Synonyms: Tezacaftor, TRIKAFTA COMPONENT TEZACAFTOR, SYMKEVI COMPONENT TEZACAFTOR, tezacaftorum, Tezacaftor (VX-661), Tezacaftor [USAN], Alyftrek, Kaftrio, Symdeko, Tezacaftor; VX-661
Related forms of this compound
2,2,3,3-tetradeuterio-1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide C26H27F3N2O6
1-(2,2-difluoro-1,3-benzodioxol-5-yl)-N-[1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)indol-5-yl]cyclopropane-1-carboxamide C26H27F3N2O6

Also listed as

Tezacaftor, >95% (HPLC) TRC CAS 1152311-62-0
Tezacaftor Mikromol CAS 1152311-62-0
Tezacaftor/ 99.69% (existing batch purity) TargetMol CAS 1152311-62-0
VX–661 GLPBio CAS 1152311-62-0
Tezacaftor 99% Ambeed CAS 1152311-62-0
1-(2,2-Difluoro-1,3-benzodioxol-5-yl)-N-[1-[(2R)-2,3-dihydroxypropyl]-6-fluoro-2-(2-hydroxy-1,1-dimethylethyl)-1H-indol-5-yl]-cyclopropanecarboxamide, 99%, 99% Chemat CAS 1152311-62-0
Tezacaftor, 99.94% MedChemExpress CAS 1152311-62-0
Tezacaftor (Standard) MedChemExpress CAS 1152311-62-0