1-Deoxy-1-(methylamino)-D-glucitol (3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)m ethyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)phosphonate
cas: 265121-04-8 — see every product listed under this CAS number, including other names
1-Deoxy-1-(methylamino)-D-glucitol (3-(((2R,3S)-2-((1R)-1-(3,5-bis(trifluoromethyl)phenyl)ethoxy)-3-(4-fluorophenyl)-4-morpholinyl)m ethyl)-2,5-dihydro-5-oxo-1H-1,2,4-triazol-1-yl)phosphonate (CAS 265121-04-8) is a chemical reagent available from Chemat. Available pack sizes: 250mg, 100mg, 500mg, 1000mg, 2000mg. Offered by: Biosynth.
| brand | Biosynth |
|---|---|
| catalog number | FD46503-250mg |
| cas | 265121-04-8 |
| size | 250mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Biosynth | 250mg | price on request | |
| Biosynth | 100mg | price on request | |
| Biosynth | 500mg | price on request | |
| Biosynth | 1000mg | price on request | |
| Biosynth | 2000mg | price on request |
properties
| category | Research Chemicals |
|---|---|
| purity | No data |
| delivery time | 1-2 weeks |
Fosaprepitant dimeglumine is an organoammonium salt obtained by reaction of fosaprepitant with two equivalents of 1-deoxy-1-(methylamino)-D-glucitol. A substance P/neurokinin 1 (NK1) receptor antagonist. Aprepitant is a selective high-affinity antagonist of human substance P/neurokinin 1 (NK1) receptors. Aprepitant has little or no affinity for serotonin (5-HT3), dopamine, and corticosteroid receptors, the targets of existing therapies for chemotherapy-induced nausea and vomiting and postoperative nausea and vomiting. It has a role as a prodrug, an antiemetic and a neurokinin-1 receptor antagonist. It contains a fosaprepitant(2-).
Source: ChEBI
| Molecular formula | C37H56F7N6O16P |
|---|---|
| Molecular weight | 1004.8 g/mol |
| IUPAC name | [3-[[(2R,3S)-2-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-3-(4-fluorophenyl)morpholin-4-yl]methyl]-5-oxo-4H-1,2,4-triazol-1-yl]phosphonic acid;bis((2R,3R,4R,5S)-6-(methylamino)hexane-1,2,3,4,5-pentol) |
| InChIKey | VRQHBYGYXDWZDL-OOZCZQCLSA-N |
| SMILES | C[C@H](C1=CC(=CC(=C1)C(F)(F)F)C(F)(F)F)O[C@@H]2[C@@H](N(CCO2)CC3=NN(C(=O)N3)P(=O)(O)O)C4=CC=C(C=C4)F.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O.CNC[C@@H]([C@H]([C@@H]([C@@H](CO)O)O)O)O |
Computed by PubChem (NCBI)