10058–F4
cas: 403811-55-2 — see every product listed under this CAS number, including other names
10058–F4 (CAS 403811-55-2) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio.
| brand | GLPBio |
|---|---|
| catalog number | GC17295-10 |
| cas | 403811-55-2 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 662.57 Pln | |
| GLPBio | 5mg | 559.60 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 587.68 Pln | |
| GLPBio | 50mg | 1158.70 Pln |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
10058-F4 is a member of the class of thiazolidinones that is 2-sulfanylidene-1,3-thiazolidin-4-one which is substituted at position 5 by a (4-ethylphenyl)methylidene group. It is a cell permeable inhibitor of c-Myc-Max dimerization and exhibits antitumour effects in vivo. It downregulates c-Myc expression and upregulates CDK inhibitors, p21 and p27 resulting in the inhibition of proliferation, induction of apoptosis and cell cycle arrest in G0/G1 phase. It has a role as an antineoplastic agent and an apoptosis inducer. It is a thiazolidinone and an olefinic compound.
Source: ChEBI
| Molecular formula | C12H11NOS2 |
|---|---|
| Molecular weight | 249.4 g/mol |
| IUPAC name | (5E)-5-[(4-ethylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one |
| InChIKey | SVXDHPADAXBMFB-JXMROGBWSA-N |
| SMILES | CCC1=CC=C(C=C1)/C=C/2\C(=O)NC(=S)S2 |
Computed by PubChem (NCBI)
Synonyms:
10058-F4 compound, 5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one, 5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone, (5E)-5-(4-ethylbenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one, (5E)-5-[(4-ethylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, 5-[(4-ethylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, (E)-5-(4-Ethylbenzylidene)-2-mercaptothiazol-4(5H)-one, orb1225110, 4-Thiazolidinone, 5-[(4-ethylphenyl)methylene]-2-thioxo-, Tox21_500046