Products 403811-55-2
CAS 403811-55-2 appears in our catalog under these names: 10058-F4/ 99.82% (existing batch purity), 10058–F4, 10058-F4 , 5-(4-Ethylbenzylidene)rhodanine, >97.0%(HPLC), 10058-F4. Offered by: TargetMol, GLPBio, Thermo Scientific (Alfa Aesar), TCI, Chemat. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 500mg, 10mM (in 1ml dmso), 1mg.
10058-F4 is a member of the class of thiazolidinones that is 2-sulfanylidene-1,3-thiazolidin-4-one which is substituted at position 5 by a (4-ethylphenyl)methylidene group. It is a cell permeable inhibitor of c-Myc-Max dimerization and exhibits antitumour effects in vivo. It downregulates c-Myc expression and upregulates CDK inhibitors, p21 and p27 resulting in the inhibition of proliferation, induction of apoptosis and cell cycle arrest in G0/G1 phase. It has a role as an antineoplastic agent and an apoptosis inducer. It is a thiazolidinone and an olefinic compound.
Source: ChEBI
| Molecular formula | C12H11NOS2 |
|---|---|
| Molecular weight | 249.4 g/mol |
| IUPAC name | (5E)-5-[(4-ethylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one |
| InChIKey | SVXDHPADAXBMFB-JXMROGBWSA-N |
| SMILES | CCC1=CC=C(C=C1)/C=C/2\C(=O)NC(=S)S2 |
Computed by PubChem (NCBI)
Synonyms:
10058-F4 compound, 5-(4-ethylbenzylidene)-2-thioxothiazolidin-4-one, 5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone, (5E)-5-(4-ethylbenzylidene)-2-mercapto-1,3-thiazol-4(5H)-one, (5E)-5-[(4-ethylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, 5-[(4-ethylphenyl)methylidene]-2-sulfanylidene-1,3-thiazolidin-4-one, (E)-5-(4-Ethylbenzylidene)-2-mercaptothiazol-4(5H)-one, orb1225110, 4-Thiazolidinone, 5-[(4-ethylphenyl)methylene]-2-thioxo-, Tox21_500046