1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-, ethanesulfonate (1:1), 98%, 98%

cas: 656247-18-6 — see every product listed under this CAS number, including other names

1H-Indole-6-carboxylic acid, 2,3-dihydro-3-[[[4-[methyl[2-(4-methyl-1-piperazinyl)acetyl]amino]phenyl]amino]phenylmethylene]-2-oxo-, methyl ester, (3Z)-, ethanesulfonate (1:1), 98%, 98% (CAS 656247-18-6) is a chemical reagent available from Chemat. Available pack sizes: 100mg, 250mg, 1g, 5g, 10g, 25g, 50g. Offered by: Chemat.

• 2D
• 3D

Nintedanib esylate is an organosulfonate salt obtained by combining nintedanib with one molar equivalent of ethanesulfonic acid. A kinase inhibitor used for the treatment of idiopathic pulmonary fibrosis and cancer. It has a role as an antifibrotic agent, an antineoplastic agent, a tyrosine kinase inhibitor, an angiogenesis inhibitor, a fibroblast growth factor receptor antagonist and a vascular endothelial growth factor receptor antagonist. It contains a nintedanib(1+).

Source: ChEBI

Identity

Molecular formula	C33H39N5O7S
Molecular weight	649.8 g/mol
IUPAC name	ethanesulfonic acid;methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate
InChIKey	ZNMRDZZRAFJOKY-UHFFFAOYSA-N
SMILES	CCS(=O)(=O)O.CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O

Computed by PubChem (NCBI)

Synonyms: Nintedanib esylate, Nintedanib Ethanesulfonate Salt, Nintedanib ethanesulfonate, OFEV, Nintedanib Esilate, Nintedanib esylate [USAN], Nintedanib esylate (USAN), Ofev (TN), Nintedanib ethanesulfonate (JAN), NINTEDANIB ETHANESULFONATE [JAN]

Isomers (same molecular formula)

2-[9,10-dimethoxy-4-oxo-2-(2,4,6-trimethylphenyl)imino-6,7-dihydropyrimido[6,1-a]isoquinolin-3-yl]ethylurea;4-methylbenzenesulfonic acid C₃₃H₃₉N₅O₇S