Products 656247-18-6
CAS 656247-18-6 appears in our catalog under these names: Nintedanib Ethanesulfonate (Intedanib Ethanesulfonate), Nintedanib Esylate, >95% (HPLC), Nintedanib Esilate, Nintedanib esylate/ 99.96% (existing batch purity), Nintedanib ethanesulfonate. Offered by: Chemat Brand, TRC, Mikromol, TargetMol, Biosynth. Available pack sizes: on request, 100mg, 250mg, 25mg, 5mg, 10mg, 50mg, 200mg.
Nintedanib esylate is an organosulfonate salt obtained by combining nintedanib with one molar equivalent of ethanesulfonic acid. A kinase inhibitor used for the treatment of idiopathic pulmonary fibrosis and cancer. It has a role as an antifibrotic agent, an antineoplastic agent, a tyrosine kinase inhibitor, an angiogenesis inhibitor, a fibroblast growth factor receptor antagonist and a vascular endothelial growth factor receptor antagonist. It contains a nintedanib(1+).
Source: ChEBI
| Molecular formula | C33H39N5O7S |
|---|---|
| Molecular weight | 649.8 g/mol |
| IUPAC name | ethanesulfonic acid;methyl 2-hydroxy-3-[N-[4-[methyl-[2-(4-methylpiperazin-1-yl)acetyl]amino]phenyl]-C-phenylcarbonimidoyl]-1H-indole-6-carboxylate |
| InChIKey | ZNMRDZZRAFJOKY-UHFFFAOYSA-N |
| SMILES | CCS(=O)(=O)O.CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N=C(C3=CC=CC=C3)C4=C(NC5=C4C=CC(=C5)C(=O)OC)O |
Computed by PubChem (NCBI)