4H-Pyrido[1,2-a]pyrimidine-2-carboxamide, N-[[6-[[(cyclohexylmethyl)amino]methyl]imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxo-, 98%, 98%
cas: 2499663-01-1 — see every product listed under this CAS number, including other names
4H-Pyrido[1,2-a]pyrimidine-2-carboxamide, N-[[6-[[(cyclohexylmethyl)amino]methyl]imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxo-, 98%, 98% (CAS 2499663-01-1) is a chemical reagent available from Chemat. Available pack sizes: 50mg, 100mg. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch12V8GO-50mg |
| cas | 2499663-01-1 |
| size | 50mg |
| availability | 5g |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat | 50mg | 1821.20 Pln | |
| Chemat | 100mg | 3054.80 Pln |
properties
| purity | 98% |
|---|---|
| delivery time | 3 weeks |
STM2457 is a secondary carboxamide resulting from the formal condensation of the carboxy group of 4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylic acid with the primary amino group of 1-[2-(aminomethyl)imidazo[1,2-a]pyridin-6-yl]-N-(cyclohexylmethyl)methanamine. It is a highly potent and selective first-in-class small molecule inhibitor of METTL3 (N6-adenosine-methyltransferase 70 kDa subunit) enzyme activity and exhibits anti-leukaemic activity. It has a role as an EC 2.1.1.348 (mRNA m6A methyltransferase) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a secondary carboxamide, a pyridopyrimidine, an imidazopyridine and a secondary amino compound.
Source: ChEBI
| Molecular formula | C25H28N6O2 |
|---|---|
| Molecular weight | 444.5 g/mol |
| IUPAC name | N-[[6-[(cyclohexylmethylamino)methyl]imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxopyrido[1,2-a]pyrimidine-2-carboxamide |
| InChIKey | OBERVORNENYOLE-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)CNCC2=CN3C=C(N=C3C=C2)CNC(=O)C4=CC(=O)N5C=CC=CC5=N4 |
Computed by PubChem (NCBI)