STM2457
cas: 2499663-01-1 — see every product listed under this CAS number, including other names
STM2457 (CAS 2499663-01-1) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 10mg, 25mg, 400mg, 5mg, 10mM (in 1ml dmso), 50mg. Offered by: GLPBio, Biosynth.
| brand | GLPBio |
|---|---|
| catalog number | GC19771-1 |
| cas | 2499663-01-1 |
| size | 1mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 1mg | 737.45 Pln | |
| GLPBio | 10mg | 1565.90 Pln | |
| GLPBio | 25mg | 2342.87 Pln | |
| GLPBio | 400mg | 12583.80 Pln | |
| GLPBio | 5mg | 1097.85 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 1163.38 Pln | |
| GLPBio | 50mg | 3166.63 Pln | |
| Biosynth | 25mg | price on request | |
| Biosynth | 50mg | price on request |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
STM2457 is a secondary carboxamide resulting from the formal condensation of the carboxy group of 4-oxo-4H-pyrido[1,2-a]pyrimidine-2-carboxylic acid with the primary amino group of 1-[2-(aminomethyl)imidazo[1,2-a]pyridin-6-yl]-N-(cyclohexylmethyl)methanamine. It is a highly potent and selective first-in-class small molecule inhibitor of METTL3 (N6-adenosine-methyltransferase 70 kDa subunit) enzyme activity and exhibits anti-leukaemic activity. It has a role as an EC 2.1.1.348 (mRNA m6A methyltransferase) inhibitor, an antineoplastic agent and an apoptosis inducer. It is a secondary carboxamide, a pyridopyrimidine, an imidazopyridine and a secondary amino compound.
Source: ChEBI
| Molecular formula | C25H28N6O2 |
|---|---|
| Molecular weight | 444.5 g/mol |
| IUPAC name | N-[[6-[(cyclohexylmethylamino)methyl]imidazo[1,2-a]pyridin-2-yl]methyl]-4-oxopyrido[1,2-a]pyrimidine-2-carboxamide |
| InChIKey | OBERVORNENYOLE-UHFFFAOYSA-N |
| SMILES | C1CCC(CC1)CNCC2=CN3C=C(N=C3C=C2)CNC(=O)C4=CC(=O)N5C=CC=CC5=N4 |
Computed by PubChem (NCBI)