5-((2-Fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, 99+%

cas: 1168091-68-6 — see every product listed under this CAS number, including other names

5-((2-Fluoro-4-iodophenyl)amino)-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide, 99+% (CAS 1168091-68-6) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 10mg, 25mg, 50mg, 100mg, 250mg, 2mg, 5mg. Offered by: BLDpharm, Fluorochem.

brandBLDpharm
catalog numberBD333077-1mg
cas1168091-68-6
size1mg
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Available pack sizes

brand size price
BLDpharm 1mg 253.27 Pln
BLDpharm 10mg 753.09 Pln
BLDpharm 25mg 1269.58 Pln
BLDpharm 50mg 1902.69 Pln
BLDpharm 100mg 2996.75 Pln
BLDpharm 250mg 5273.72 Pln
Fluorochem 1mg 320.74 Pln
Fluorochem 2mg 424.87 Pln
Fluorochem 5mg 768.50 Pln
Fluorochem 10mg 1242.29 Pln
Fluorochem 25mg 2038.88 Pln
Fluorochem 50mg 3210.35 Pln
Fluorochem 100mg 5048.24 Pln

properties

purity99+%
delivery time 1-2 weeks
Structural formula: {0} (CAS {1})

GDC-0623 is a member of the class of imidazopyridines that is imidazo[1,5-a]pyridine substituted by (2-fluoro-4-iodophenyl)amino and (2-hydroxyethoxy)aminoacyl groups at positions 5 and 6. It is a potent ATP non-competitive inhibitor of MEK1 (Ki = 0.13nM) and also has efficacy against both mutant BRAF and mutant KRAS. It is in clinical development for treatment of patients with locally advanced or metastatic solid tumors. It has a role as an antineoplastic agent, an apoptosis inducer and an EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor. It is a primary alcohol, an organoiodine compound, an imidazopyridine, a substituted aniline, a secondary amino compound, a hydroxamic acid ester and a member of monofluorobenzenes.

Source: ChEBI

Identity
Molecular formulaC16H14FIN4O3
Molecular weight456.21 g/mol
IUPAC name5-(2-fluoro-4-iodoanilino)-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-6-carboxamide
InChIKeyRFWVETIZUQEJEF-UHFFFAOYSA-N
SMILESC1=CC(=C(C=C1I)F)NC2=C(C=CC3=CN=CN32)C(=O)NOCCO

Computed by PubChem (NCBI)

Synonyms: RFWVETIZUQEJEF-UHFFFAOYSA-N, orb1223413, orb1300414, s7553

Also listed as

GDC-0623 (5-((2-Fluoro-4-Iodophenyl)amino)-N-(2-Hydroxyethoxy)imidazo(1,5-a)pyridine-6-Carboxamide) Chemat Brand CAS 1168091-68-6
GDC–0623 GLPBio CAS 1168091-68-6
GDC-0623/ 98.95% (existing batch purity) TargetMol CAS 1168091-68-6
GDC 0623 Biosynth CAS 1168091-68-6
GDC-0623, 98.74% MedChemExpress CAS 1168091-68-6
GDC-0623, 99+% Ambeed CAS 1168091-68-6