6β-Hydroxycortisone, 95%
cas: 16355-28-5 — see every product listed under this CAS number, including other names
6β-Hydroxycortisone, 95% (CAS 16355-28-5) is a chemical reagent available from Chemat. Available pack sizes: 5mg. Offered by: Fluorochem.
| brand | Fluorochem |
|---|---|
| catalog number | F925245-5MG |
| cas | 16355-28-5 |
| size | 5mg |
| availability | In Stock China |
Documents:
Safety Data Sheet (MSDS)
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Fluorochem | 5mg | 2169.05 Pln |
properties
| purity | 95% |
|---|---|
| dual use | No |
| currency | EUR |
| delivery time | 2-3 weeks |
| category | Odczynniki chemiczne |
6beta-hydroxycortisone is a C21-steroid that is cortisone bearing an additional hydroxy substituent at the 6beta-position. It is produced as a metabolite of cortisol by cytochrome p450-3A4 (CYP3A4, an important enzyme involved in the metabolism of a variety of exogenous and endogenous compounds) and can be used to detect moderate and potent CYP3A4 inhibition in vivo. It has a role as a probe and a human metabolite. It is a primary alpha-hydroxy ketone, a tertiary alpha-hydroxy ketone, a 17alpha-hydroxy steroid, a 21-hydroxy steroid, a 6beta-hydroxy steroid, a 20-oxo steroid, an 11-oxo steroid, a 3-oxo-Delta(4) steroid and a C21-steroid. It is functionally related to a cortisone.
Source: ChEBI
| Molecular formula | C21H28O6 |
|---|---|
| Molecular weight | 376.4 g/mol |
| IUPAC name | (6R,8S,9S,10R,13S,14S,17R)-6,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,6,7,8,9,12,14,15,16-decahydrocyclopenta[a]phenanthrene-3,11-dione |
| InChIKey | BCHHPSBWEQCAPG-WTCKOWDJSA-N |
| SMILES | C[C@]12CCC(=O)C=C1[C@@H](C[C@@H]3[C@@H]2C(=O)C[C@]4([C@H]3CC[C@@]4(C(=O)CO)O)C)O |
Computed by PubChem (NCBI)
Synonyms:
6beta-Hydroxycortisone, Hydroxycortisone, 6beta-, 6b-Hydroxycortisone, Pregn-4-ene-3,11,20-trione, 6,17,21-trihydroxy-, (6beta)-, Corticosterone, 11-dehydro-6beta,17-dihydroxy-, 6beta,17alpha,21-Trihydroxy-4-pregnene-3,11,20-trione, 6beta,17,21-trihydroxypregn-4-ene-3,11,20-trione, 6|A-Hydroxycortisone, 4-pregnene-6beta,17alpha,21-triol-3,11,20-trione, 6beta-17alpha,21-trihydroxypregn-4-ene-3,11,20-trione