A 485

cas: 1889279-16-6 — see every product listed under this CAS number, including other names

A 485 (CAS 1889279-16-6) is a chemical reagent available from Chemat. Available pack sizes: 50mg, 5mg, 10mg, 25mg, 100mg. Offered by: Biosynth.

brandBiosynth
catalog numberBA166476-50mg
cas1889279-16-6
size50mg
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properties

categoryLife Sciences
sub-category 1Ligands
sub-category 2Enzyme Modulators
purityNo data
delivery time1-2 weeks
Structural formula: {0} (CAS {1})

A-485 is a potent and selective catalytic inhibitor of p300/CBP with IC50s of 9.8 nM and 2.6 nM for p300 and CBP histone acetyltransferase (HAT), respectively.

Source: ChEBI

Identity
Molecular formulaC25H24F4N4O5
Molecular weight536.5 g/mol
IUPAC nameN-[(4-fluorophenyl)methyl]-2-[(3R)-6-(methylcarbamoylamino)-2',4'-dioxospiro[1,2-dihydroindene-3,5'-1,3-oxazolidine]-3'-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]acetamide
InChIKeyVRVJKILQRBSEAG-LFPIHBKWSA-N
SMILESC[C@@H](C(F)(F)F)N(CC1=CC=C(C=C1)F)C(=O)CN2C(=O)[C@]3(CCC4=C3C=CC(=C4)NC(=O)NC)OC2=O

Computed by PubChem (NCBI)

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