Products 1889279-16-6

CAS 1889279-16-6 appears in our catalog under these names: A-485, 95%, A-485/ 98.32% (existing batch purity), A–485, A 485, A-485 97%. Offered by: Combi-blocks, TargetMol, GLPBio, Biosynth, Ambeed. Available pack sizes: 250mg, 100mg, 1mg, 2mg, 5mg, 10mg, 25mg, 50mg.

A-485, 95%
Combi-blocks
  • size: 250mg, 100mg
  • Variants: 2
View product
A-485/ 98.32% (existing batch purity)
TargetMol
  • size: 1mg, 2mg, 5mg, 10mg
  • Variants: 7
from 757.88
View product
A–485
GLPBio
  • size: 1mg, 10mg, 10mM (in 1ml dmso), 5mg
  • Variants: 5
from 774.90
View product
A 485
Biosynth
  • size: 50mg, 5mg, 10mg, 25mg
  • Variants: 5
View product
A-485 97%
Ambeed
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 375.94
View product
A-485, 97%, 97%
Chemat
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 6
from 381.20
View product
A-485, 99.87%
MedChemExpress
  • size: 100 mg, 10mM/1mL, 1 mg, 5 mg
  • Variants: 6
from 649.42
View product
N-(4-Fluorobenzyl)-2-((R)-5-(3-methylureido)-2',4'-dioxo-2,3-dihydrospiro[indene-1,5'-oxazolidin]-3'-yl)-N-((S)-1,1,1-trifluoropropan-2-yl)acetamide, 97%
Fluorochem
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 5
from 700.81
View product
Structural formula: {0} (CAS {1})

A-485 is a potent and selective catalytic inhibitor of p300/CBP with IC50s of 9.8 nM and 2.6 nM for p300 and CBP histone acetyltransferase (HAT), respectively.

Source: ChEBI

Identity
Molecular formulaC25H24F4N4O5
Molecular weight536.5 g/mol
IUPAC nameN-[(4-fluorophenyl)methyl]-2-[(3R)-6-(methylcarbamoylamino)-2',4'-dioxospiro[1,2-dihydroindene-3,5'-1,3-oxazolidine]-3'-yl]-N-[(2S)-1,1,1-trifluoropropan-2-yl]acetamide
InChIKeyVRVJKILQRBSEAG-LFPIHBKWSA-N
SMILESC[C@@H](C(F)(F)F)N(CC1=CC=C(C=C1)F)C(=O)CN2C(=O)[C@]3(CCC4=C3C=CC(=C4)NC(=O)NC)OC2=O

Computed by PubChem (NCBI)

Synonyms: orb1308704, orb1941062, VRVJKILQRBSEAG-LFPIHBKWSA-N, N-(4-fluorobenzyl)-2-((R)-5-(3-methylureido)-2',4'-dioxo-2,3-dihydrospi