Products 2627-69-2
CAS 2627-69-2 appears in our catalog under these names: 5-Aminoimidazole-4-carboxamide-1-b-D-rib, ofuranose, 500 mg, AICAR, 95%, 5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside, >95% (HPLC), AICAR/ 99.69% (existing batch purity), AICAR. Offered by: Roth, Combi-blocks, TRC, TargetMol, GLPBio. Available pack sizes: 500mg, 5g, 1g, 250mg, 10g, 50mg, 25mg, 200mg.
Acadesine is a 1-ribosylimidazolecarboxamide in which the carboxamide group is situated at position 4 of the imidazole ring, which is further substituted at position 5 by an amino group. A purine nucleoside analogue and activator of AMP-activated protein kinase, it is is used for the treatment of acute lymphoblastic leukemia and is reported to have cardioprotective effects. It has a role as an antineoplastic agent and a platelet aggregation inhibitor. It is an aminoimidazole, a 1-ribosylimidazolecarboxamide and a nucleoside analogue.
Source: ChEBI
| Molecular formula | C9H14N4O5 |
|---|---|
| Molecular weight | 258.23 g/mol |
| IUPAC name | 5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide |
| InChIKey | RTRQQBHATOEIAF-UUOKFMHZSA-N |
| SMILES | C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N)C(=O)N |
Computed by PubChem (NCBI)