ARS-1630
cas: 1698055-86-5 — see every product listed under this CAS number, including other names
ARS-1630 (CAS 1698055-86-5) is a chemical reagent available from Chemat. Available pack sizes: 1mg, 5mg, 10mg, 25mg, 50mg, 100mg, 200mg. Offered by: Chemat.
| brand | Chemat |
|---|---|
| catalog number | Ch12EOLM-1mg |
| cas | 1698055-86-5 |
| size | 1mg |
| availability | 0.2g |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat | 1mg | 290.00 Pln | |
| Chemat | 5mg | 621.20 Pln | |
| Chemat | 10mg | 866.00 Pln | |
| Chemat | 25mg | 1403.60 Pln | |
| Chemat | 50mg | 1946.00 Pln | |
| Chemat | 100mg | 2685.20 Pln | |
| Chemat | 200mg | 3746.00 Pln |
properties
| delivery time | 3 weeks |
|---|
ARS-1620 is a qinazoline derivative carrying chloro and fluoro substituents at positions 6 and 8 respectively, a 2-fluoro-6-hydroxyphenyl group at position 7, and a 4-(prop-2-enoyl)piperazin-1-yl group at position 4. A potent, selective, and orally bioavailable covalent KRAS-G12C inhibitor, it inhibits the protein coding gene KRAS (Kirsten rat sarcoma virus) with high potency in cells and animals. It has a role as an antiviral agent, an inhibitor and an antineoplastic agent.
Source: ChEBI
| Molecular formula | C21H17ClF2N4O2 |
|---|---|
| Molecular weight | 430.8 g/mol |
| IUPAC name | 1-[4-[6-chloro-8-fluoro-7-(2-fluoro-6-hydroxyphenyl)quinazolin-4-yl]piperazin-1-yl]prop-2-en-1-one |
| InChIKey | ZRPZPNYZFSJUPA-UHFFFAOYSA-N |
| SMILES | C=CC(=O)N1CCN(CC1)C2=NC=NC3=C(C(=C(C=C32)Cl)C4=C(C=CC=C4F)O)F |
Computed by PubChem (NCBI)