Products 2100284-59-9
CAS 2100284-59-9 appears in our catalog under these names: AZ3451/ 98.12% (existing batch purity), AZ–3451, AZ 3451, (S)-2-(6-Bromobenzo[d][1,3]dioxol-5-yl)-N-(4-cyanophenyl)-1-(1-cyclohexylethyl)-1H-benzo[d]imidazole-5-carboxamide, 98%, 98%, AZ3451, 99.84%. Offered by: TargetMol, GLPBio, Biosynth, Chemat, MedChemExpress. Available pack sizes: 5mg, 10mg, 25mg, 50mg, 100mg, 200mg, 1mg, 25 mg.
AZ3451 is a member of the class of benzimidazoles that is 1H-benzimidazole substituted by (1S)-1-cyclohexylethyl, 6-bromo-1,3-benzodioxol-5-yl, and 4-(cyanoanilino)acyl groups at positions 1, 2 and 5, respectively. It is an allosteric modulator of protease-activated receptor 2 (IC50 = 23 nM) and exhibits anti-osteoarthritis properties. It has a role as an autophagy inducer, a PAR2 negative allosteric modulator and an anti-inflammatory agent. It is a secondary carboxamide, a nitrile, a member of benzimidazoles, an organobromine compound and a member of benzodioxoles.
Source: ChEBI
| Molecular formula | C30H27BrN4O3 |
|---|---|
| Molecular weight | 571.5 g/mol |
| IUPAC name | 2-(6-bromo-1,3-benzodioxol-5-yl)-N-(4-cyanophenyl)-1-[(1S)-1-cyclohexylethyl]benzimidazole-5-carboxamide |
| InChIKey | FJAOGFGHTPYADT-SFHVURJKSA-N |
| SMILES | C[C@@H](C1CCCCC1)N2C3=C(C=C(C=C3)C(=O)NC4=CC=C(C=C4)C#N)N=C2C5=CC6=C(C=C5Br)OCO6 |
Computed by PubChem (NCBI)