Products 1231929-97-7

CAS 1231929-97-7 appears in our catalog under these names: N-{5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-1,3-benzodiazol-5-yl)pyrimidin-2-amine, 97%, Abemaciclib, >95% (HPLC), Abemaciclib, Abemaciclib/ 99.87% (existing batch purity), LY2835219 free base. Offered by: Combi-blocks, TRC, Mikromol, TargetMol, GLPBio. Available pack sizes: 250mg, 1g, 5g, 100mg, 10mg, 50mg, 5mg, 25mg.

N-{5-[(4-Ethylpiperazin-1-yl)methyl]pyridin-2-yl}-5-fluoro-4-(7-fluoro-3-isopropyl-2-methyl-1,3-benzodiazol-5-yl)pyrimidin-2-amine, 97%
Combi-blocks
  • size: 250mg, 1g, 5g
  • Variants: 3
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Abemaciclib, >95% (HPLC)
TRC
  • size: 100mg, 10mg, 50mg
  • Variants: 3
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Abemaciclib
Mikromol, Biosynth
  • size: 250mg, 0,5g, 0,25g, 1g
  • Variants: 6
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Abemaciclib/ 99.87% (existing batch purity)
TargetMol
  • size: 5mg, 10mg, 25mg, 50mg
  • Variants: 7
from 499.07
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LY2835219 free base
GLPBio
  • size: 10mg, 200mg, 5mg, 50mg
  • Variants: 4
from 667.25
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Abemaciclib, 98%
Thermo Scientific (Acros)
  • size: 100MG
  • Variants: 1
from 1331.88
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Abemaciclib 99%
Ambeed
  • size: 50mg, 100mg, 250mg, 1g
  • Variants: 5
from 175.69
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Abemaciclib, 99.97%
MedChemExpress
  • size: 10 mg, 100 mg, 500 mg, 200 mg
  • Variants: 8
from 407.93
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Abemaciclib (Standard), 99.94%
MedChemExpress
  • size: 10 mg, 100 mg, 50 mg, 25 mg
  • Variants: 5
from 839.82
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Abemaciclib, 99%
Fluorochem
  • size: 1g, 5g
  • Variants: 2
from 279.09
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Structural formula: {0} (CAS {1})

Abemaciclib is a cell cycle inhibitor selective for CDK4/6 with IC50 of 2 nM and 10 nM in cell-free assays, respectively.

Source: ChEBI

Identity
Molecular formulaC27H32F2N8
Molecular weight506.6 g/mol
IUPAC nameN-[5-[(4-ethylpiperazin-1-yl)methyl]-2-pyridinyl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine
InChIKeyUZWDCWONPYILKI-UHFFFAOYSA-N
SMILESCCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F

Computed by PubChem (NCBI)

Synonyms: Abemaciclib, Verzenio, Verzenios, abemaciclibum, Abemaciclib (ly2835219), s5716, Abemaciclib [USAN:INN], Abemaciclib,LY2835219, rimidin-2-amine, Verzenio (TN)