Ac-Tyr-Val-Ala-Asp-chloromethylketone

cas: 178603-78-6 — see every product listed under this CAS number, including other names

Ac-Tyr-Val-Ala-Asp-chloromethylketone (CAS 178603-78-6) is a chemical reagent available from Chemat. Available pack sizes: 25mg, 10mg, 50mg. Offered by: Biosynth.

brandBiosynth
catalog numberFA111035-25mg
cas178603-78-6
size25mg
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Available pack sizes

brand size price
Biosynth 25mg price on request
Biosynth 10mg price on request
Biosynth 50mg price on request

properties

categoryResearch Chemicals
sub-category 1Sourcing
purityNo data
delivery time4-6 weeks
Structural formula: {0} (CAS {1})

Ac-Tyr-Val-Ala-Asp-chloromethylketone is a tetrapeptide composed of L-tyrosine, L-valine, L-alanine, and L-aspartic acid joined in sequence by peptide linkages and in which the amino terminus in substituted by an acetyl group and the carboxy terminus is substituted by a chloromethyl group. It has a role as a neuroprotective agent, a nephroprotective agent and an EC 3.4.22.36 (caspase-1) inhibitor. It is an organochlorine compound and a tetrapeptide. It is functionally related to a L-valine, a L-alanine, a L-aspartic acid and a N-acetyl-L-tyrosine.

Source: ChEBI

Identity
Molecular formulaC24H33ClN4O8
Molecular weight541.0 g/mol
IUPAC name(3S)-3-[[(2S)-2-[[(2S)-2-[[(2S)-2-acetamido-3-(4-hydroxyphenyl)propanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]-5-chloro-4-oxopentanoic acid
InChIKeyUOUBHJRCKHLGFB-DGJUNBOTSA-N
SMILESC[C@@H](C(=O)N[C@@H](CC(=O)O)C(=O)CCl)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CC1=CC=C(C=C1)O)NC(=O)C

Computed by PubChem (NCBI)

Synonyms: acs.jmedchem.1c00409_ST.801, Ac-YVAD-CMK, Caspase-1 Inhibitor II, Ac-Tyr-Val-Ala-Asp-chloromethylketone, acetyl-Tyr-Val-Ala-Asp-chloromethylketone, Ac-Tyr-Val-Ala-Asp-chloromethyl ketone, N-acetyl-tyr-val-ala-asp-chloromethyl ketone, C24H33ClN4O8, Ac-Tyr-Val-Ala-Asp-chloromethyl-ketone, acetyl-Tyr-Val-Ala-Asp chloromethylketone

Also listed as

Caspase-1 Inhibitor II, >95% (HPLC) TRC CAS 178603-78-6
Ac-YVAD-CMK/ 99.49% (existing batch purity) TargetMol CAS 178603-78-6
Ac–YVAD–CMK GLPBio CAS 178603-78-6
Ac-Tyr-Val-Lys-Asp-H (aldehyde) Biosynth CAS 178603-78-6
Ac-Tyr-Val-Ala-Asp-CH2Cl Biosynth CAS 178603-78-6
Ac-YVAD-cmk 98% Ambeed CAS 178603-78-6
Caspase-1 Inhibitor II 1PC X 5MG Sigma-Aldrich CAS 178603-78-6
Caspase-1 Inhibitor II, 98%, 98% Chemat CAS 178603-78-6
Ac-YVAD-cmk, 98.94% MedChemExpress CAS 178603-78-6
Ac-YVAD-CMK, ≥95% Fluorochem CAS 178603-78-6