Adagrasib

cas: 2326521-71-3 — see every product listed under this CAS number, including other names

Adagrasib (CAS 2326521-71-3) is a chemical reagent available from Chemat. Available pack sizes: on request. Offered by: Chemat Brand.

brandChemat Brand
catalog numberULK031010
cas2326521-71-3
sizeon request
availability Do potwierdzenia przez Chemat|To be confirmed by Chemat
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purityNo data
categoryChemicals
delivery timeTo be confirmed by Chemat
Structural formula: {0} (CAS {1})

Adagrasib (MRTX849) is an oral, small-molecule KRAS inhibitor developed by Mirati Therapeutics. KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations.

Source: ChEBI

Identity
Molecular formulaC32H35ClFN7O2
Molecular weight604.1 g/mol
IUPAC name2-[(2S)-4-[7-(8-chloronaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]-1-(2-fluoroprop-2-enoyl)piperazin-2-yl]acetonitrile
InChIKeyPEMUGDMSUDYLHU-ZEQRLZLVSA-N
SMILESCN1CCC[C@H]1COC2=NC3=C(CCN(C3)C4=CC=CC5=C4C(=CC=C5)Cl)C(=N2)N6CCN([C@H](C6)CC#N)C(=O)C(=C)F

Computed by PubChem (NCBI)

Synonyms: Adagrasib, KRAZATI, Kras G12C inhibitor MRTX849, Adagrasib [USAN], Adagrasib (MRTX849), Krazati (TN), ADAGRASIB [INN], Adagrasib (USAN/INN), ADAGRASIB [WHO-DD], C32H35ClFN7O2

Also listed as

Adagrasib/ 99.84% (existing batch purity) TargetMol CAS 2326521-71-3
MRTX849 GLPBio CAS 2326521-71-3
Adagrasib 98% Ambeed CAS 2326521-71-3
2-Piperazineacetonitrile, 4-[7-(8-chloro-1-naphthalenyl)-5,6,7,8-tetrahydro-2-[[(2S)-1-methyl-2-pyrrolidinyl]methoxy]pyrido[3,4-d]pyrimidin-4-yl]-1-(2-fluoro-1-oxo-2-propen-1-yl)-, (2S)-, 98%, 98% Chemat CAS 2326521-71-3
Adagrasib, 99.96% MedChemExpress CAS 2326521-71-3