MRTX849
cas: 2326521-71-3 — see every product listed under this CAS number, including other names
MRTX849 (CAS 2326521-71-3) is a chemical reagent available from Chemat. Available pack sizes: 10mg, 100mg, 1g, 25mg, 5mg, 10mM (in 1ml dmso), 50mg, 500mg. Offered by: GLPBio, Biosynth.
| brand | GLPBio |
|---|---|
| catalog number | GC38400-10 |
| cas | 2326521-71-3 |
| size | 10mg |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| GLPBio | 10mg | 788.94 Pln | |
| GLPBio | 100mg | 2642.42 Pln | |
| GLPBio | 1g | 11685.14 Pln | |
| GLPBio | 25mg | 1233.59 Pln | |
| GLPBio | 5mg | 690.65 Pln | |
| GLPBio | 10mM (in 1ml dmso) | 835.75 Pln | |
| GLPBio | 50mg | 1888.86 Pln | |
| GLPBio | 500mg | 7458.65 Pln | |
| Biosynth | 5mg | price on request | |
| Biosynth | 10mg | price on request | |
| Biosynth | 25mg | price on request |
properties
| purity | No data |
|---|---|
| delivery time | To be confirmed by Chemat |
Adagrasib (MRTX849) is an oral, small-molecule KRAS inhibitor developed by Mirati Therapeutics. KRAS mutations are highly common in cancer and account for approximately 85% of all RAS family mutations.
Source: ChEBI
| Molecular formula | C32H35ClFN7O2 |
|---|---|
| Molecular weight | 604.1 g/mol |
| IUPAC name | 2-[(2S)-4-[7-(8-chloronaphthalen-1-yl)-2-[[(2S)-1-methylpyrrolidin-2-yl]methoxy]-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-4-yl]-1-(2-fluoroprop-2-enoyl)piperazin-2-yl]acetonitrile |
| InChIKey | PEMUGDMSUDYLHU-ZEQRLZLVSA-N |
| SMILES | CN1CCC[C@H]1COC2=NC3=C(CCN(C3)C4=CC=CC5=C4C(=CC=C5)Cl)C(=N2)N6CCN([C@H](C6)CC#N)C(=O)C(=C)F |
Computed by PubChem (NCBI)