Afatinib (dimaleate) (Standard)

cas: 850140-73-7 — see every product listed under this CAS number, including other names

Afatinib (dimaleate) (Standard) (CAS 850140-73-7) is a chemical reagent available from Chemat. Available pack sizes: 10 mg, 50 mg, 25 mg, 100 mg, 5 mg. Offered by: MedChemExpress.

brand	MedChemExpress
catalog number	HY-10261AR-10 mg
cas	850140-73-7
size	10 mg
availability	Get quote

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Available pack sizes

brand	size	price
MedChemExpress	10 mg	928.06 Pln
MedChemExpress	50 mg	2061.19 Pln
MedChemExpress	25 mg	1415.68 Pln
MedChemExpress	100 mg	2855.32 Pln
MedChemExpress	5 mg	621.55 Pln

properties

delivery time	over 3 weeks
purity	no data

Afatinib dimaleate is a maleate salt obtained by combining afatinib with two molar equivalents of maleic acid. Used for the first-line treatment of patients with metastatic non-small cell lung cancer. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It contains an afatinib.

Source: ChEBI

Identity
Molecular formula	C₃₂H₃₃ClFN₅O₁₁
Molecular weight	718.1 g/mol
IUPAC name	bis((Z)-but-2-enedioic acid);(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide
InChIKey	USNRYVNRPYXCSP-JUGPPOIOSA-N
SMILES	CN(C/C=C/C(=O)NC1=C(C=C2N=CN=C(C2=C1)NC3=CC(=C(C=C3)F)Cl)O[C@@H]4COCC4)C.C(=C\C(=O)O)\C(=O)O.C(=C\C(=O)O)\C(=O)O

Computed by PubChem (NCBI)

Synonyms: AFATINIB DIMALEATE, Gilotrif, Afatinib maleate, Giotrif, Afatinib (diMaleate), Afatinib dimaleate [USAN], Giotrif (TN), Afatinib maleate (JAN), AFATINIB DIMALEATE [MI], Afatinib (BIBW2992) Dimaleate