CAS 850140-73-7 appears in our catalog under these names: Afatinib Dimaleate, Afatinib Dimaleate, >95% (HPLC), Afatinib Dimaleate/ 99.66% (existing batch purity), Afatinib dimaleate, Afatinib dimaleate 98%. Offered by: Chemat Brand, TRC, Mikromol, TargetMol, GLPBio. Available pack sizes: on request, 1g, 50mg, 250mg, 5mg, 10mg, 25mg, 100mg.
Afatinib dimaleate is a maleate salt obtained by combining afatinib with two molar equivalents of maleic acid. Used for the first-line treatment of patients with metastatic non-small cell lung cancer. It has a role as an antineoplastic agent and a tyrosine kinase inhibitor. It contains an afatinib.
Source: ChEBI
| Molecular formula | C32H33ClFN5O11 |
|---|---|
| Molecular weight | 718.1 g/mol |
| IUPAC name | bis((Z)-but-2-enedioic acid);(E)-N-[4-(3-chloro-4-fluoroanilino)-7-[(3S)-oxolan-3-yl]oxyquinazolin-6-yl]-4-(dimethylamino)but-2-enamide |
| InChIKey | USNRYVNRPYXCSP-JUGPPOIOSA-N |
| SMILES | CN(C/C=C/C(=O)NC1=C(C=C2N=CN=C(C2=C1)NC3=CC(=C(C=C3)F)Cl)O[C@@H]4COCC4)C.C(=C\C(=O)O)\C(=O)O.C(=C\C(=O)O)\C(=O)O |
Computed by PubChem (NCBI)