Amrubicin
cas: 110267-81-7 — see every product listed under this CAS number, including other names
Amrubicin (CAS 110267-81-7) is a chemical reagent available from Chemat. Available pack sizes: on request, 0,5mg, 1mg, 5mg. Offered by: Chemat Brand, TRC, GLPBio.
| brand | Chemat Brand |
|---|---|
| catalog number | ULA273002 |
| cas | 110267-81-7 |
| size | on request |
| availability | Do potwierdzenia przez Chemat|To be confirmed by Chemat |
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Available pack sizes
| brand | size | price | |
|---|---|---|---|
| Chemat Brand | on request | price on request | |
| TRC | 0,5mg | price on request | |
| TRC | 1mg | price on request | |
| GLPBio | 1mg | 910.63 Pln | |
| GLPBio | 5mg | 1912.26 Pln |
properties
| purity | No data |
|---|---|
| category | Chemicals |
| delivery time | To be confirmed by Chemat |
Amrubicin is a synthetic anthracycline antibiotic with molecular formula C25H25NO9. A specific inhibitor of topoisomerase II, it is used (particularly as the hydrochloride salt) in the treatment of cancer, especially lung cancer, where it is a prodrug for the active metabolite, ambrucinol. It has a role as a topoisomerase II inhibitor, an antineoplastic agent and a prodrug. It is a quinone, an anthracycline antibiotic, a primary amino compound, a member of tetracenes and a methyl ketone.
Source: ChEBI
| Molecular formula | C25H25NO9 |
|---|---|
| Molecular weight | 483.5 g/mol |
| IUPAC name | (7S,9S)-9-acetyl-9-amino-7-[(2S,4S,5R)-4,5-dihydroxyoxan-2-yl]oxy-6,11-dihydroxy-8,10-dihydro-7H-tetracene-5,12-dione |
| InChIKey | VJZITPJGSQKZMX-XDPRQOKASA-N |
| SMILES | CC(=O)[C@]1(C[C@@H](C2=C(C1)C(=C3C(=C2O)C(=O)C4=CC=CC=C4C3=O)O)O[C@H]5C[C@@H]([C@@H](CO5)O)O)N |
Computed by PubChem (NCBI)