Products 913076-54-7

CAS 913076-54-7 is the registry number for Amrubicin maleate. Offered by: Biosynth. Available pack sizes: 5mg, 1mg, 10mg.

Amrubicin maleate
Biosynth
  • size: 5mg, 1mg, 10mg
  • Variants: 3
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Structural formula: {0} (CAS {1})

Amrubicin is a synthetic anthracycline antibiotic with molecular formula C25H25NO9. A specific inhibitor of topoisomerase II, it is used (particularly as the hydrochloride salt) in the treatment of cancer, especially lung cancer, where it is a prodrug for the active metabolite, ambrucinol. It has a role as a topoisomerase II inhibitor, an antineoplastic agent and a prodrug. It is a quinone, an anthracycline antibiotic, a primary amino compound, a member of tetracenes and a methyl ketone.

Source: ChEBI

Identity
Molecular formulaC25H25NO9
Molecular weight483.5 g/mol
IUPAC name(7S,9S)-9-acetyl-9-amino-7-[(2S,4S,5R)-4,5-dihydroxyoxan-2-yl]oxy-6,11-dihydroxy-8,10-dihydro-7H-tetracene-5,12-dione
InChIKeyVJZITPJGSQKZMX-XDPRQOKASA-N
SMILESCC(=O)[C@]1(C[C@@H](C2=C(C1)C(=C3C(=C2O)C(=O)C4=CC=CC=C4C3=O)O)O[C@H]5C[C@@H]([C@@H](CO5)O)O)N

Computed by PubChem (NCBI)

Synonyms: Amrubicin, amrubicina, amrubicine, amrubicinum, Amrubicin(SM-5887), Amrubicin [INN], Amrubicin [USAN:INN], Amrubicin maleate, AMRUBICIN [MI], Amrubicin (USAN/INN)
Related forms of this compound
(7S,9S)-9-acetyl-9-amino-7-[(2S,4S,5R)-4,5-dihydroxyoxan-2-yl]oxy-6,11-dihydroxy-8,10-dihydro-7H-tetracene-5,12-dione C25H25NO9
Isomers (same molecular formula)
(7S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-7,8-dihydrotetracene-5,12-dione C25H25NO9