Aprocitentan, 99.55%

cas: 1103522-45-7 — see every product listed under this CAS number, including other names

Aprocitentan, 99.55% (CAS 1103522-45-7) is a chemical reagent available from Chemat. Available pack sizes: 25 mg, 100 mg, 5 mg, 1 mg, 50 mg, 10 mg, 10mM/1mL. Offered by: MedChemExpress.

brandMedChemExpress
catalog numberHY-15895-25 mg
cas1103522-45-7
size25 mg
availability In stock
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Available pack sizes

brand size price
MedChemExpress 25 mg 2502.37 Pln
MedChemExpress 100 mg 4629.32 Pln
MedChemExpress 5 mg 1067.38 Pln
MedChemExpress 1 mg 505.45 Pln
MedChemExpress 50 mg 3459.04 Pln
MedChemExpress 10 mg 1485.34 Pln
MedChemExpress 10mM/1mL 1257.78 Pln

properties

delivery time 1-2 weeks
purity99.55%
Structural formula: {0} (CAS {1})

ACT-132577 is a member of the class of sulfamides in which one of the amino groups of sulfonamide is substituted by a 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl group. An active metabolite of macitentan (obtained by oxidative depropylation), an orphan drug used for the treatment of pulmonary arterial hypertension. It has a role as an antihypertensive agent, a drug metabolite, an endothelin receptor antagonist and a xenobiotic metabolite. It is an aromatic ether, an organobromine compound, a member of pyrimidines and a member of sulfamides. It is functionally related to an ethylene glycol.

Source: ChEBI

Identity
Molecular formulaC16H14Br2N6O4S
Molecular weight546.2 g/mol
IUPAC name5-(4-bromophenyl)-4-[2-(5-bromopyrimidin-2-yl)oxyethoxy]-6-(sulfamoylamino)pyrimidine
InChIKeyDKULOVKANLVDEA-UHFFFAOYSA-N
SMILESC1=CC(=CC=C1C2=C(N=CN=C2OCCOC3=NC=C(C=N3)Br)NS(=O)(=O)N)Br

Computed by PubChem (NCBI)

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